- 专利标题: Compositions and methods for treating IgE-mediated disorders
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申请号: US13860500申请日: 2013-04-10
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公开(公告)号: US09617348B2公开(公告)日: 2017-04-11
- 发明人: John R. Desjarlais , Seung Y. Chu , Holly M. Horton , Matthew J. Bernett
- 申请人: Xencor, Inc.
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 代理机构: Morgan, Lewis & Bockius, LLP
- 代理商 Robin M. Silva; Louis T. Nguyen
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/42 ; C07K16/46
摘要:
The present invention relates to immunoglobulins that bind IgE and FcγRIIb with high affinity, said compositions being capable of inhibiting cells that express membrane-anchored IgE. Such compositions are useful for treating IgE-mediated disorders, including allergies and asthma.
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