发明授权
- 专利标题: Heptamer-type small guide nucleic acids inducing apoptosis of human leukemia cells
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申请号: US14241580申请日: 2012-08-24
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公开(公告)号: US09617538B2公开(公告)日: 2017-04-11
- 发明人: Masayuki Nashimoto , Masuhiro Takahashi , Miwako Narita , Tetsuo Yoshida , Tatsuya Miyazawa
- 申请人: Masayuki Nashimoto , Masuhiro Takahashi , Miwako Narita , Tetsuo Yoshida , Tatsuya Miyazawa
- 申请人地址: JP Niigata JP Niigata
- 专利权人: NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCE,NIIGATA UNIVERSITY
- 当前专利权人: NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCE,NIIGATA UNIVERSITY
- 当前专利权人地址: JP Niigata JP Niigata
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2011-185594 20110829
- 国际申请: PCT/JP2012/071503 WO 20120824
- 国际公布: WO2013/031704 WO 20130307
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C12N15/113 ; A61K31/7105
摘要:
There is provided a heptamer-type small guide nucleic acid that comprises any of the 7-base sequences of SEQ ID NOS: 1 to 15, and induces apoptosis of human leukemia cells. A leukemia therapeutic agent containing the heptamer-type small guide nucleic acid as an active ingredient is also provided. The novel heptamer-type sg nucleic acid can induce apoptosis of human leukemia cells.
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