Management of power consumption in large computing clusters is disclosed herein. According to an aspect, a method includes using a power manager to receive, via a communication interface, information associated with the cluster of computing nodes. The method includes determining whether a switch is coupled to an inactive computing node of the cluster of computing nodes based on the received information. Further, the method includes communicating a command to the switch to remove power supplied to a switch port of the switch coupled to the inactive computing node in response to determining that the switch is coupled to an inactive computing node of the cluster of computing nodes.