- 专利标题: Gene cluster for biosynthesis of cornexistin and hydroxycornexistin
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申请号: US14441215申请日: 2013-11-13
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公开(公告)号: US09631212B2公开(公告)日: 2017-04-25
- 发明人: Oskar Zelder , Birgit Hoff , Hartwig Schroeder , Andrea Molt , Holger Hartmann , Klaus Ditrich , Michael Breuer , Rüdiger Reingrubber , Jakob Weber
- 申请人: BASF SE
- 申请人地址: DE Ludwigshafen
- 专利权人: BASF SE
- 当前专利权人: BASF SE
- 当前专利权人地址: DE Ludwigshafen
- 代理机构: Marshall, Gerstein & Borun LLP
- 优先权: EP12193405 20121120; EP13182735 20130903
- 国际申请: PCT/IB2013/060093 WO 20131113
- 国际公布: WO2014/080316 WO 20140530
- 主分类号: C12N15/80
- IPC分类号: C12N15/80 ; C12P17/04 ; C12N15/67 ; C07D307/93 ; C12N15/52 ; C07K14/37 ; A01N37/46 ; A01N63/04 ; A01N37/42
摘要:
The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.
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