- 专利标题: Lipid bilayer carrier for drugs or imaging agents
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申请号: US13809469申请日: 2011-07-08
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公开(公告)号: US09642802B2公开(公告)日: 2017-05-09
- 发明人: Sander Langereis , Holger Gruell , Mariska De Smet , Erica Maria Gerarda Aussems-Custers , Johan Lub
- 申请人: Sander Langereis , Holger Gruell , Mariska De Smet , Erica Maria Gerarda Aussems-Custers , Johan Lub
- 申请人地址: NL Eindhoven
- 专利权人: Koninklijke Philips N.V.
- 当前专利权人: Koninklijke Philips N.V.
- 当前专利权人地址: NL Eindhoven
- 优先权: EP10169325 20100713
- 国际申请: PCT/IB2011/053047 WO 20110708
- 国际公布: WO2012/007886 WO 20120119
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K41/00 ; A61K31/704 ; A61K49/10 ; A61K49/18
摘要:
Disclosed are carriers for drugs and/or MR imaging agents having a lipid bilayer shell comprising a phospholipid having two terminal alkyl chains, one being a short chain having a chain length of at most seven carbon atoms, the other being a long chain having a chain length of at least fifteen carbon atoms. The mixed long/short chain phospholipids serve to tune the release properties of the carrier. Preferred phospholipids are phosphatidylcholines.
公开/授权文献
- US20130108551A1 LIPID BILAYER CARRIER FOR DRUGS OR IMAGING AGENTS 公开/授权日:2013-05-02
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