Invention Grant
- Patent Title: Substituted pyridines as sodium channel blockers
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Application No.: US13996082Application Date: 2011-12-21
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Publication No.: US09656959B2Publication Date: 2017-05-23
- Inventor: Chiyou Ni , Minnie Park , Bin Shao , Laykea Tafesse , Jiangchao Yao , Mark A. Youngman , Xiaoming Zhou
- Applicant: Chiyou Ni , Minnie Park , Bin Shao , Laykea Tafesse , Jiangchao Yao , Mark A. Youngman , Xiaoming Zhou
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiying Yang
- International Application: PCT/IB2011/003137 WO 20111221
- International Announcement: WO2012/085650 WO 20120628
- Main IPC: C07D213/75
- IPC: C07D213/75 ; C07D401/02 ; C07D401/12 ; C07D401/14 ; C07D213/76 ; C07D213/81 ; C07D413/12
Abstract:
The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20140005212A1 Substituted Pyridines as Sodium Channel Blockers Public/Granted day:2014-01-02
Information query
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