- 专利标题： Aminoglycoside and azole compositions and methods
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申请号： US14281659申请日： 2014-05-19
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公开(公告)号： US09669044B2公开(公告)日： 2017-06-06
- 发明人: Jon Y. Takemoto , Cheng-wei Tom Chang , Sanjib K. Shrestha , Michelle Grilley
- 申请人： Jon Y. Takemoto , Cheng-wei Tom Chang , Sanjib K. Shrestha , Michelle Grilley
- 申请人地址： US UT Logan
- 专利权人： Utah State University
- 当前专利权人： Utah State University
- 当前专利权人地址： US UT Logan
- 主分类号： A61K31/7036
- IPC分类号： A61K31/7036 ; A61K31/496 ; A61K31/4196 ; A61K31/506 ; A61K31/415 ; A61K31/365 ; A01N43/16
摘要：
The present invention relates to novel fungicidal compound including an aminoglycoside analog having certain substituents at the 6 position of ring III that exhibit improved antifungal activity but possess minimal antibacterial properties in combination with fungicidal azoles. The aminoglycoside compounds are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
公开/授权文献
- US20140256665A1 Aminoglycoside and Azole Compositions and Methods 公开/授权日：2014-09-11