A method of driving a display panel includes steps of generating a plurality of load signals, of which at least one load signal has a different timing from the rest of the load signals, generating data voltages synchronized to low periods of the load signals and outputting the data voltages to data lines. Accordingly, the data voltages synchronized to each of the load signals can be outputted to each of the data lines. A color coordinate problem occurring when applying a RGBW type may be solved by setting a charging time of a white sub-pixel different from the rest of the sub-pixels. Thus, display quality of a display apparatus including the display panel may be improved.