Invention Grant
- Patent Title: Methods for preparing anti-viral nucleotide analogs
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Application No.: US15135357Application Date: 2016-04-21
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Publication No.: US09676804B2Publication Date: 2017-06-13
- Inventor: Denise A. Colby , Andrew Anthony Martins , Benjamin James Roberts , Robert William Scott , Nicole S. White
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: GILEAD SCIENCES, INC.
- Current Assignee: GILEAD SCIENCES, INC.
- Current Assignee Address: US CA Foster City
- Agent Joel Silver
- Main IPC: C07F9/6561
- IPC: C07F9/6561
Abstract:
Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
Public/Granted literature
- US20160311840A1 METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS Public/Granted day:2016-10-27
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