- 专利标题： Tricyclic compounds as alpha-7 nicotinic acetylcholine receptor ligands
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申请号： US15317546申请日： 2015-06-05
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公开(公告)号： US09708323B2公开(公告)日： 2017-07-18
- 发明人: Ivar M. McDonald , F. Christopher Zusi , Richard E. Olson
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 James Epperson
- 国际申请： PCT/US2015/034569 WO 20150605
- 国际公布： WO2015/191403 WO 20151217
- 主分类号： C07D471/18
- IPC分类号： C07D471/18
摘要：
The disclosure provides compounds of formula I including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.