Invention Grant
- Patent Title: Cyclopropanamine compound and use thereof
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Application No.: US15203522Application Date: 2016-07-06
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Publication No.: US09718814B2Publication Date: 2017-08-01
- Inventor: Shigemitsu Matsumoto , Yasushi Hattori , Masashi Toyofuku , Shinji Morimoto , Takuto Kojima , Tomohiro Kaku , Mitsuhiro Ito
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2014-082057 20140411
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14 ; C07D213/82 ; C07D333/38 ; C07D285/135 ; C07D409/14 ; C07D231/12 ; C07D413/14 ; C07D277/56 ; C07D409/12 ; C07D307/79 ; C07D407/12 ; C07D231/14 ; C07D333/40 ; C07D285/08 ; C07D413/12 ; C07D307/81

Abstract:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
Public/Granted literature
- US20160311814A1 CYCLOPROPANAMINE COMPOUND AND USE THEREOF Public/Granted day:2016-10-27
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