Invention Grant
- Patent Title: Nanofluidic channels with gradual depth change for reducing entropic barrier of biopolymers
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Application No.: US15074701Application Date: 2016-03-18
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Publication No.: US09776184B2Publication Date: 2017-10-03
- Inventor: Qinghuang Lin , Gustavo A. Stolovitzky , Chao Wang , Deqiang Wang
- Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
- Applicant Address: US NY Armonk
- Assignee: International Business Machines Corporation
- Current Assignee: International Business Machines Corporation
- Current Assignee Address: US NY Armonk
- Agency: Tutunjian & Bitetto, P.C.
- Agent Vazken Alexanian
- Main IPC: B01L3/00
- IPC: B01L3/00 ; G01N27/447 ; G01N33/487

Abstract:
A device for passing a biopolymer molecule includes a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel. The surface relief structure includes a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer.
Public/Granted literature
- US20160199833A1 NANOFLUIDIC CHANNELS WITH GRADUAL DEPTH CHANGE FOR REDUCING ENTROPIC BARRIER OF BIOPOLYMERS Public/Granted day:2016-07-14
Information query
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