Invention Grant
- Patent Title: Small interfering RNA and pharmaceutical composition and method for inhibiting galectin-12 expression and/or enhancing lipolysis containing the same
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Application No.: US15322878Application Date: 2015-08-05
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Publication No.: US09777273B2Publication Date: 2017-10-03
- Inventor: Yen-Ju Lin , Jui-Wen Huang , Fu-Tong Liu , Huan-Yuan Chen , Wei-Chen Hsieh
- Applicant: Industrial Technology Research Institute , Academia Sinica
- Applicant Address: TW Hsinchu TW Taipei
- Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE,ACADEMIA SINICA
- Current Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE,ACADEMIA SINICA
- Current Assignee Address: TW Hsinchu TW Taipei
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/US2015/043761 WO 20150805
- International Announcement: WO2016/022648 WO 20160211
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
A small interfering RNA is provided. The small interfering RNA consists of a passenger strand and a guide strand, wherein the sequence of the passenger strand comprises the sequence of SEQ ID NO. 7, and the sequence of the guide strand comprises the sequence of SEQ ID NO. 8, wherein the small interfering RNA is capable of inhibiting galectin-12 expression.
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