- 专利标题: Process for the detection and early serotyping of the dengue virus
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申请号: US14113631申请日: 2012-04-26
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公开(公告)号: US09778260B2公开(公告)日: 2017-10-03
- 发明人: Frederic Bedin , Sandrine Busseret , Marine Steidel
- 申请人: Frederic Bedin , Sandrine Busseret , Marine Steidel
- 申请人地址: FR Marcy l'Etoile
- 专利权人: BIOMERIEUX
- 当前专利权人: BIOMERIEUX
- 当前专利权人地址: FR Marcy l'Etoile
- 代理机构: Oliff PLC
- 优先权: FR1153916 20110506
- 国际申请: PCT/FR2012/050926 WO 20120426
- 国际公布: WO2012/153031 WO 20121115
- 主分类号: C07K16/10
- IPC分类号: C07K16/10 ; C12Q1/70 ; C07K14/005 ; C12N7/00 ; A61K39/00 ; G01N33/569 ; G01N33/68
摘要:
Disclosed is a process for in vitro detection of an infection by a dengue virus in an individual, including the following steps: contacting a blood sample from the individual with a ligand specific to the NS1 protein of said dengue virus, to capture NS1 protein if it is present in the blood sample, said ligand being immobilized on a solid support; detecting the presence of NS1 protein via a mass spectrometry reading; and if NS1 protein is detected, concluding that the individual has been infected by dengue virus.