Invention Grant
- Patent Title: Anti-NGF compositions and use thereof
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Application No.: US13309295Application Date: 2011-12-01
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Publication No.: US09783602B2Publication Date: 2017-10-10
- Inventor: Benjamin H. Dutzar , Brian R. Kovacevich , Patricia Dianne McNeill , Danielle M. Mitchell , Ethan W. Ojala , Pei Fan , Jens Billgren , Erica A. Stewart , Corinne C. Akatsuka , Betty Yu-Ching Chang , John A. Latham , Leon F. Garcia-Martinez
- Applicant: Benjamin H. Dutzar , Brian R. Kovacevich , Patricia Dianne McNeill , Danielle M. Mitchell , Ethan W. Ojala , Pei Fan , Jens Billgren , Erica A. Stewart , Corinne C. Akatsuka , Betty Yu-Ching Chang , John A. Latham , Leon F. Garcia-Martinez
- Applicant Address: US NV Las Vegas
- Assignee: ALDERBIO HOLDINGS LLC
- Current Assignee: ALDERBIO HOLDINGS LLC
- Current Assignee Address: US NV Las Vegas
- Agency: LeClairRyan A Professional Corporation
- Agent Robin L. Teskin
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/22 ; A61K45/06 ; C07K16/28 ; A61K39/00

Abstract:
The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.
Public/Granted literature
- US09499611B2 Anti-NGF compositions and use thereof Public/Granted day:2016-11-22
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