- 专利标题： Methods and compositions for the clinical derivation of an allogenic cell and therapeutic uses
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申请号： US13732204申请日： 2012-12-31
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公开(公告)号： US09803176B2公开(公告)日： 2017-10-31
- 发明人: Amit Patel
- 申请人： Amit Patel
- 代理机构： Thorpe North and Western, LLP
- 代理商 Todd B. Alder
- 主分类号： C12N5/073
- IPC分类号： C12N5/073 ; C12N5/071 ; C12N5/0775 ; A61K35/51 ; C12N5/077
摘要：
Various cells, stem cells, and stem cell components, including associated methods of generating and using such cells are provided. In one aspect, for example, an isolated cell that is capable of self-renewal and culture expansion and is obtained from a subepithelial layer of a mammalian umbilical cord tissue. Such an isolated cell expresses at least three cell markers selected from CD29, CD73, CD90, CD166, SSEA4, CD9, CD44, CD146, or CD105, and does not express at least three cell markers selected from CD45, CD34, CD14, CD79, CD106, CD86, CD80, CD19, CD117, Stro-1, or HLA-DR.
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