The present disclosure relates to an interference screw for creating an interference fit between a bone tunnel and tissue. The screw includes a threaded body having a proximal end, distal end, and thread extending around the threaded body between the proximal and distal ends. A supporting spline extends along a cannulation through the threaded body. The supporting spline is engagable with a delivery device. The screw further includes at least one opening defined by a surface between threads of the threaded body. A ratio of open surface area to closed surface area defines the opening and is selected such that, when torsionally loaded, the screw does not exhibit plastic deformation when inserted into an undersized bone tunnel. The screw further includes a tapered tip extending from the distal end of the threaded body. The tapered tip has a thread extending at least partway around the tapered tip.