- 专利标题: GLS1 inhibitors for treating disease
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申请号: US14791186申请日: 2015-07-02
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公开(公告)号: US09809588B2公开(公告)日: 2017-11-07
- 发明人: Maria Emilia Di Francesco , Philip Jones , Timothy Heffernan , Matthew M. Hamilton , Zhijun Kang , Michael J. Soth , Jason P. Burke , Kang Le , Christopher Lawrence Carroll , Wylie S. Palmer , Richard Lewis , Timothy McAfoos , Barbara Czako , Gang Liu , Jay Theroff , Zachary Herrera , Anne Yau
- 申请人: Board of Regents, The University of Texas System
- 申请人地址: US TX Austin
- 专利权人: Board of Regents, The University of Texas System
- 当前专利权人: Board of Regents, The University of Texas System
- 当前专利权人地址: US TX Austin
- 代理商 Dennis A. Bennett; Cynthia Hathaway
- 主分类号: C07D417/14
- IPC分类号: C07D417/14 ; C07D417/06 ; C07D403/06 ; C07D405/14 ; C07D403/14 ; C07D493/08 ; C07D401/14 ; A61K31/433 ; A61K31/501 ; A61K31/497 ; A61K45/06 ; A61K31/4439 ; A61K31/454 ; A61K31/4192 ; A61K31/444
摘要:
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
公开/授权文献
- US20160009704A1 GLS1 INHIBITORS FOR TREATING DISEASE 公开/授权日:2016-01-14
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