A method for interference cancellation is provided. The method includes: determining, by a first base station, a channel parameter from a transmit antenna of a second base station to a receive antenna of the first base station; receiving, by the first base station, a first signal using a first resource, where the first signal includes: a first interference signal and an uplink wanted signal, and the first interference signal is an interference signal generated when a downlink second signal is sent by the second base station by using the first resource; receiving, by the first base station, reconstruction information that is of the second signal and that is sent by the second base station; and determining, by the first base station, the first interference signal in the first signal according to the channel parameter and the reconstruction information of the second signal, and canceling the first interference signal.