A device (100) for the treatment of depression, anxiety and pain, the device comprising: a plurality of adjacent dots (11) or other shapes, each comprising means for providing a signal being sensible by a touch sense, the signal comprising mechanical signal and/or electrical signal and/or temperature signal and/or magnetic signal; and a controller (32) for executing each of the means independently, for providing pre-programmed shapes (30, 40, 40A, 40B, 42, 46, 48, 50, 52, 54) being sensible by the touch sense, thereby allowing treating the depression, anxiety and pain by generating to the brain, signals resembling the pre-programmed shapes (30, 40, 40A, 40B, 42, 46, 48, 50, 52, 54) through the signals being sensible by the touch sense.