- 专利标题： 10-substituted colchicinoids as potent anticancer agents
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申请号： US15519054申请日： 2015-10-14
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公开(公告)号： US09868695B2公开(公告)日： 2018-01-16
- 发明人: Ram A. Vishwakarma , Sandip B. Bharate , Ajay Kumar , Baljinder Singh , Ashok Kumar , Shashi Bhushan , Abid Hamid , Prashant Joshi , Santosh K. Guru , Suresh Kumar , Aashiq Hussain , Asif K. Qazi , Sonali S. Bharate , Parduman Sharma , Ajit K. Saxena , Dilip M. Mondhe , Girish Mahajan , Zahoor Wani
- 申请人： Council of Scientific & Industrial Research
- 申请人地址： IN New Delhi
- 专利权人： Council of Scientific & Industrial Research
- 当前专利权人： Council of Scientific & Industrial Research
- 当前专利权人地址： IN New Delhi
- 代理机构： Locke Lord LLP
- 代理商 Nicholas J. DiCeglie, Jr.
- 优先权： IN2929/DEL/2014 20141014
- 国际申请： PCT/IN2015/050135 WO 20151014
- 国际公布： WO2016/059650 WO 20160421
- 主分类号： C07C233/41
- IPC分类号： C07C233/41 ; C07C231/12 ; A61K31/165
摘要：
The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.
公开/授权文献
- US20170226051A1 10-SUBSTITUTED COLCHICINOIDS AS POTENT ANTICANCER AGENTS 公开/授权日：2017-08-10
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