- 专利标题： C-linked heterocycloaklyl substituted pyrimidines and their uses
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申请号： US14928034申请日： 2015-10-30
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公开(公告)号： US09868720B2公开(公告)日： 2018-01-16
- 发明人: Frederick Cohen , Snahel Patel
- 申请人： Genentech, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理商 Jonathan Duffield
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D401/14 ; C07D405/14 ; C07D403/14 ; C07D471/04 ; C07D493/08 ; A61K31/5377 ; A61K31/5386 ; A61K31/553 ; A61K35/30 ; C07D409/14 ; C07D413/14 ; C07D487/04 ; C07D491/08 ; C07D491/107 ; C07D498/08
摘要：
The present invention provides for pyrimidine compounds of Formula I-I and embodiments thereof In Formula I-I in which R1, R2, R3, R4, R5, R6, m, n and the “het” ring are as described herein. Also provided are pharmaceutical compositions comprising compounds of Formula I and methods of using such compounds and compositions.
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