Embodiments of the present invention provide a display apparatus and a method of driving the display apparatus. The display apparatus includes a display panel, a visual state acquiring module, and a visual acuity correcting module. The display panel includes M×N sub-pixels arranged in a matrix for displaying an image signal. The visual acuity correcting module is disposed in a display area of the display panel and includes a plurality of light blocking structures, the plurality of light blocking structures form M×N grid holes in one-to-one correspondence with the sub-pixels, and the visual acuity correcting module is configured to adjust sizes of the grid holes.