The present invention relates to the field of communications technologies, and discloses a method, an apparatus, and a system for suppressing interference in a massive multiple-input multiple-output system, which overcome a disadvantage of sensitivity to a backhaul delay during an inter-cell interference cancellation process in an existing massive multiple-input multiple-output system. A specific embodiment of the present invention includes: obtaining channel correlation matrixes of all links, and further calculating a combined outer precoder set according to the channel correlation matrixes, where each combined outer precoder includes at least one outer precoder, and the outer precoder is a semi-unitary matrix and is not sensitive to a backhaul delay. Technical solutions of the present invention are mainly applied to a process of processing interference in a massive multiple-input multiple-output system.