- 专利标题： Labeled circular DNA molecules for analysis of DNA topology, and topoisomerases and for drug screening
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申请号： US15286046申请日： 2016-10-05
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公开(公告)号： US09890416B2公开(公告)日： 2018-02-13
- 发明人: Fenfei Leng
- 申请人： Fenfei Leng
- 申请人地址： US FL Miami
- 专利权人： THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
- 当前专利权人： THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
- 当前专利权人地址： US FL Miami
- 代理机构： Saliwanchik, Lloyd & Eisenschenk
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/00 ; C12P19/34
摘要：
The present invention provides labeled circular plasmid DNA molecules for studying DNA topology and topoisomerases. The molecules of the present invention also provide tools for high throughput drug screening for inhibitors of DNA gyrases and DNA topoisomerases for anticancer drug discovery and antibiotics discovery.
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