A door garnish mounting device for a mounting a door garnish to a door of a vehicle includes a frame, door alignment arms extending from the frame, and a garnish applicator mounted to the frame. The door alignment arms having datum points configured to engage corresponding vehicle datum points of the vehicle proximate to a mounting location of the door garnish to the vehicle to align the frame with the door of the vehicle. The garnish applicator includes a pressing device configured to engage and press against the door garnish, a first actuator configured to press the pressing device against the door garnish, and a second actuator configured to move the pressing device along the door garnish.