Invention Grant
- Patent Title: Anti-blood dendritic cell antigen 2 antibodies and uses thereof
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Application No.: US14649297Application Date: 2013-12-10
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Publication No.: US09902775B2Publication Date: 2018-02-27
- Inventor: Justin A. Caravella , Ellen A. Garber Stark , Dania Mounir Rabah , Frederick R. Taylor
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2013/074208 WO 20131210
- International Announcement: WO2014/093396 WO 20140619
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/28
Abstract:
Antibodies and antibody fragments that bind to BDCA2 are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to induce death of a plasmacytoid dendritic cell, inhibit production or secretion of inflammatory cytokines and chemokines, and treat or prevent immunological disorders such as inflammatory and autoimmune conditions.
Public/Granted literature
- US20150299325A1 Anti-Blood Dendritic Cell Antigen 2 Antibodies And Uses Thereof Public/Granted day:2015-10-22
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