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公开(公告)号：US10335485B2
公开(公告)日：2019-07-02
申请号：US15838884
申请日：2017-12-12
Applicant: Biogen MA Inc.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K16/30
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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公开(公告)号：US20240100155A1
公开(公告)日：2024-03-28
申请号：US18165146
申请日：2023-02-06
Applicant: BIOGEN MA INC.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , A61K45/06 , C07K16/28 , C07K16/30
CPC classification number: A61K39/39558 , A61K45/06 , C07K16/2839 , C07K16/2842 , C07K16/3061 , C07K2317/24 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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公开(公告)号：US11083791B2
公开(公告)日：2021-08-10
申请号：US16441974
申请日：2019-06-14
Applicant: BIOGEN MA INC.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K16/30
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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公开(公告)号：US11571477B2
公开(公告)日：2023-02-07
申请号：US17366903
申请日：2021-07-02
Applicant: BIOGEN MA INC.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K16/30
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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Patent Agency Ranking
公开(公告)号：US09902775B2
公开(公告)日：2018-02-27
申请号：US14649297
申请日：2013-12-10
Applicant: Biogen MA Inc.
CPC classification number: C07K16/2851 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/626 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92
Abstract: Antibodies and antibody fragments that bind to BDCA2 are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to induce death of a plasmacytoid dendritic cell, inhibit production or secretion of inflammatory cytokines and chemokines, and treat or prevent immunological disorders such as inflammatory and autoimmune conditions.
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公开(公告)号：US20180362652A1
公开(公告)日：2018-12-20
申请号：US15869514
申请日：2018-01-12
Applicant: Biogen MA Inc.
Abstract: Antibodies and antibody fragments that bind to BDCA2 are disclosed. Also disclosed are methods of using the antibodies and antibody fragments to induce death of a plasmacytoid dendritic cell, inhibit production or secretion of inflammatory cytokines and chemokines, and treat or prevent immunological disorders such as inflammatory and autoimmune conditions.
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公开(公告)号：US20210401981A1
公开(公告)日：2021-12-30
申请号：US17366903
申请日：2021-07-02
Applicant: BIOGEN MA INC.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K16/30
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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公开(公告)号：US20190233530A1
公开(公告)日：2019-08-01
申请号：US16379844
申请日：2019-04-10
Applicant: UCB BIOPHARMA SPRL , BIOGEN MA INC.
Inventor： Linda C. Burkly , Janine L. Ferrant-Orgettas , Ellen A. Garber , Yen-Ming Hsu , Lihe Su , Frederick R. Taylor , Ralph Adams , Derek Thomas Brown , Andrew George Popplewell , Martyn Kim Robinson , Anthony Shock , Kerry Louise Tyson
IPC: C07K16/28 , A61K39/395 , A61K45/06
CPC classification number: C07K16/2875 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/52 , C07K2317/55 , C07K2317/71 , C07K2317/734 , C07K2317/76 , C07K2317/92
Abstract: This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions.
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公开(公告)号：US20180221480A1
公开(公告)日：2018-08-09
申请号：US15838884
申请日：2017-12-12
Applicant: Biogen MA Inc.
Inventor： Alexey A. Lugovskoy , Frederick R. Taylor , Karen McLachlan
IPC: A61K39/395 , C07K16/30 , A61K45/06 , C07K16/28
CPC classification number: A61K39/39558 , A61K45/06 , C07K16/2839 , C07K16/2842 , C07K16/3061 , C07K2317/24 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: This invention relates to alpha-4 binding antibodies, and fragments thereof.
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