- 专利标题: Inhibiting neurotransmitter reuptake
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申请号: US14776397申请日: 2014-03-10
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公开(公告)号: US09944618B2公开(公告)日: 2018-04-17
- 发明人: Elliott Richelson , Abdul H. Fauq , Paul Carlier , Christopher J. Monceaux
- 申请人: Mayo Foundation for Medical Education and Research , Virginia Tech Intellectual Properties, Inc.
- 申请人地址: US MN Rochester US VA Blacksburg
- 专利权人: Mayo Foundation for Medical Education and Research,Virginia Tech Intellectual Properties, Inc.
- 当前专利权人: Mayo Foundation for Medical Education and Research,Virginia Tech Intellectual Properties, Inc.
- 当前专利权人地址: US MN Rochester US VA Blacksburg
- 代理机构: Fish & Richardson P.C.
- 国际申请: PCT/US2014/022684 WO 20140310
- 国际公布: WO2014/159251 WO 20141002
- 主分类号: C07D333/28
- IPC分类号: C07D333/28 ; C07C259/06 ; C07C211/30 ; A61K31/138 ; C07C215/28 ; C07C215/68 ; C07C217/48 ; C07C217/62 ; C07C217/64 ; C07C233/43 ; C07C235/06 ; C07C235/08 ; C07D317/58 ; C07D319/18 ; C07D333/20 ; C07D261/08 ; C07D265/06 ; C07D267/10 ; C07D207/12 ; C07D271/06 ; C07D295/135 ; C07D295/185 ; C07D213/30 ; C07D213/61 ; C07D213/64 ; C07D213/65 ; C07C215/30 ; C07C235/14 ; C07C323/32 ; C07D205/04 ; C07D213/38 ; C07D215/06 ; C07D295/192
摘要:
This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine, serotonin, epinephrine or norepinephrine are provided as therapeutic agents for the treatment of depression or anxiety in a mammalian subject.
公开/授权文献
- US20160024044A1 INHIBITING NEUROTRANSMITTER REUPTAKE 公开/授权日:2016-01-28
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