Invention Grant
- Patent Title: Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores
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Application No.: US14234698Application Date: 2012-07-25
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Publication No.: US09957560B2Publication Date: 2018-05-01
- Inventor: Clive Gavin Brown , James Anthony Clarke , Graham Hall , Gavin Harper , Andrew John Heron , James White
- Applicant: Clive Gavin Brown , James Anthony Clarke , Graham Hall , Gavin Harper , Andrew John Heron , James White
- Applicant Address: GB Oxford
- Assignee: Oxford Nanopore Technologies Ltd.
- Current Assignee: Oxford Nanopore Technologies Ltd.
- Current Assignee Address: GB Oxford
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/GB2012/051786 WO 20120725
- International Announcement: WO2013/014451 WO 20130131
- Main IPC: C12Q1/6869
- IPC: C12Q1/6869 ; C12Q1/68 ; G01N27/447 ; G01N33/487
Abstract:
The invention relates to a new method of sequencing a double stranded target polynucleotide. The two strands of the double stranded target polynucleotide are linked by a bridging moiety. The two strands of the target polynucleotide are separated using a polynucleotide binding protein and the target polynucleotide is sequenced using a transmembrane pore.
Public/Granted literature
- US20150152492A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES Public/Granted day:2015-06-04
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