- 专利标题： Process for the preparation of 5-bromo-1,2,3-trichlorobenzene
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申请号： US15515322申请日： 2015-10-08
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公开(公告)号： US09975823B2公开(公告)日： 2018-05-22
- 发明人: Helmars Smits
- 申请人： SYNGENTA PARTICIPATIONS AG
- 申请人地址： CH Basel
- 专利权人： Syngenta Participations AG
- 当前专利权人： Syngenta Participations AG
- 当前专利权人地址： CH Basel
- 代理商 James Cueva
- 优先权： EP14188742 20141014
- 国际申请： PCT/EP2015/073219 WO 20151008
- 国际公布： WO2016/058897 WO 20160421
- 主分类号： C07C17/04
- IPC分类号： C07C17/04 ; C07C17/06 ; C07C17/12 ; C07C17/35 ; C07C17/358 ; C07C25/10
摘要：
The present invention relates to a process for the preparation of a compound of formula I (I), comprising reacting a compound of formula II (II), with a brominating agent in the presence of an acidic catalyst to a compound of formula III (III), and reacting the compound of formula III in tetrahydrofuran or 2-methyl-tetrahydrofuran with potassium tert-butoxide to a compound of formula I.
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