再颁专利
- 专利标题： Growth arrest homebox gene
- 专利标题（中）： 生长抑制家箱基因
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申请号： US09755320申请日： 2001-01-05
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公开(公告)号： USRE39219E1公开(公告)日： 2006-08-01
- 发明人: David H. Gorski , Kenneth Walsh
- 申请人： David H. Gorski , Kenneth Walsh
- 申请人地址： US OH Cleveland
- 专利权人： Case Western Reserve University
- 当前专利权人： Case Western Reserve University
- 当前专利权人地址： US OH Cleveland
- 代理机构： Calfee, Halter & Griswold LLP
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C12N15/63 ; C12N1/21 ; C12N5/10
摘要：
A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.
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