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    METABOLIC AND CARDIOPROTECTION BY THE MYOKINE FOLLISTATIN-LIKE 1 POLYPEPTIDE
    2.
    发明申请
    METABOLIC AND CARDIOPROTECTION BY THE MYOKINE FOLLISTATIN-LIKE 1 POLYPEPTIDE 有权
    由MYOKINE FOLLISTATIN-LIKE 1 POLYPEPTIDE代谢和保护

    公开(公告)号：US20100227817A1

    公开(公告)日：2010-09-09

    申请号：US12682898

    申请日：2008-10-20

    申请人： Kenneth Walsh ,  Yuichi Oshima ,  Noriyuki Ouchi

    发明人： Kenneth Walsh ,  Yuichi Oshima ,  Noriyuki Ouchi

    IPC分类号： A61K38/22 ,  A61P9/10 ,  A61P3/08

    CPC分类号： A61K38/1709 ,  Y10S514/824 ,  Y10S514/866

    摘要： Described herein are methods and compositions related to the discovery that the Follistatin-like 1 protein (Fstl-1) has metabolic and cardioprotective effects in vivo. Fstl-1 and portions and derivatives or variants thereof can be used to treat or prevent metabolic diseases or disorders and to treat or prevent cardiac damage caused by interrupted cardiac muscle blood supply.

    摘要翻译： 本文描述了与发现Follistatin样1蛋白（Fst1-1）在体内具有代谢和心脏保护作用有关的方法和组合物。 Fstl-1及其部分和衍生物或变体可用于治疗或预防代谢疾病或病症，并治疗或预防心脏肌肉供血中断引起的心脏损伤。

    Method
    3.
    发明申请
    Method 审中-公开
    方法

    公开(公告)号：US20080057521A1

    公开(公告)日：2008-03-06

    申请号：US11765745

    申请日：2007-06-20

    申请人： Martin Barnardo ,  Andrea Harmer ,  Michael Bunce ,  Robert Vaughn ,  Kenneth Walsh

    发明人： Martin Barnardo ,  Andrea Harmer ,  Michael Bunce ,  Robert Vaughn ,  Kenneth Walsh

    IPC分类号： G01N33/00

    CPC分类号： G01N33/6854 ,  G01N33/543 ,  G01N33/566 ,  Y10S435/975

    摘要： The invention provides a method of detecting the presence of anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and detecting the binding or absence of binding of antibodies to said recombinant MHC molecules. This method allows the detection and/or identification of one or more specific MHC particularly HLA allele antibodies

    摘要翻译： 本发明提供了一种检测样品中抗MHC抗体的存在的方法，包括使所述样品与一种或多种重组MHC分子或功能等同的变体，衍生物或片段接触并检测抗体与所述重组体的结合或结合 MHC分子。 该方法允许检测和/或鉴定一种或多种特异性MHC，特别是HLA等位基因抗体

    BEVERAGE LID DISPENSER
    4.
    发明申请
    BEVERAGE LID DISPENSER 审中-公开
    饮料分配器

    公开(公告)号：US20070151982A1

    公开(公告)日：2007-07-05

    申请号：US11617919

    申请日：2006-12-29

    申请人： NICHOLAS WALSH ,  KENNETH WALSH

    发明人： NICHOLAS WALSH ,  KENNETH WALSH

    IPC分类号： B65H3/00

    CPC分类号： A47F1/125 ,  A47F1/085 ,  A47F1/106 ,  A47F1/123

    摘要： The current invention is a lid dispensing device and method of use comprising a base unit, a lid holder operatively connected to the base unit, a blade operatively mounted to the base which moves between a first position and a second position, a tab secured to the blade to aid in separating lids, the blade supporting a stack of lids by engaging a first lid in the stack of lids while the blade is in the first position, and the blade allowing the first lid to fall through an aperture in the blade away from the stack of lids, and still support the remaining stack of lids as the blade moves to the second position.

    摘要翻译： 本发明是一种盖分配装置和使用方法，包括基座单元，可操作地连接到基座单元的盖保持器，可操作地安装到基座的叶片，该基座在第一位置和第二位置之间移动， 叶片以帮助分离盖子，叶片通过在叶片处于第一位置时将盖子的第一盖接合而支撑盖子堆叠，并且叶片允许第一盖子通过叶片中的孔而脱落。 盖子堆叠，并且当刀片移动到第二位置时仍然支撑剩余的盖子堆叠。

    Beverage lid dispenser
    5.
    发明申请
    Beverage lid dispenser 有权

    公开(公告)号：US20060249526A1

    公开(公告)日：2006-11-09

    申请号：US11121373

    申请日：2005-05-04

    申请人： Kenneth Walsh ,  Nicholas Walsh

    发明人： Kenneth Walsh ,  Nicholas Walsh

    IPC分类号： B65G59/00

    CPC分类号： G07F11/045 ,  A47F1/106 ,  B65G59/105 ,  G07F13/10

    摘要： The current invention is a lid dispensing device and method of use comprising a base unit, a lid holder operatively connected to the base unit, a blade operatively mounted to the base which moves between a first position and a second position, the blade supporting a stack of lids by engaging a first lid in the stack of lids while the blade is in the first position, and the blade allowing the first lid to fall through an aperture in the blade away from the stack of lids, and still support the remaining stack of lids as the blade moves to the second position.

    Growth arrest homeobox gene
    6.
    发明申请
    Growth arrest homeobox gene 审中-公开

    公开(公告)号：US20060141476A1

    公开(公告)日：2006-06-29

    申请号：US10784513

    申请日：2004-02-23

    申请人： David Gorski ,  Kenneth Walsh

    发明人： David Gorski ,  Kenneth Walsh

    IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12P21/06 ,  C12N9/99

    CPC分类号： C07K14/4703 ,  A61K38/00

    摘要： A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

    GARMENT WITH HYDROPHOBIC FOREARMS
    8.
    发明申请
    GARMENT WITH HYDROPHOBIC FOREARMS 审中-公开
    具有疏水性前体的服装

    公开(公告)号：US20080060113A1

    公开(公告)日：2008-03-13

    申请号：US11924580

    申请日：2007-10-25

    申请人： Kenneth Walsh

    发明人： Kenneth Walsh

    IPC分类号： A41B1/00 ,  A41B1/08 ,  A41D1/00 ,  A41D27/00

    CPC分类号： A41D27/10 ,  A41D31/30

    摘要： A garment comprising different portions having different performance characteristics. A preferred embodiment is a fishing shirt comprising: a body portion, said body portion being fabricated from a breathable, knitted fabric having a wicking finish; a collar portion and a yoke portion, said collar portion and said yoke portion being fabricated from a four-way stretch fabric having a wicking finish; a pair of lower sleeve portions, each of said lower sleeve portions being fabricated from a non-wicking, hydrophobic fabric; and an optional pair of underarm portions, each of said underarm portions being fabricated from a knit, anti-microbial fabric.

    摘要翻译： 一种衣服，其包括具有不同性能特征的不同部分。 优选实施例是一种钓鱼衬衫，包括：主体部分，所述主体部分由具有芯吸整理剂的透气针织物制成; 轴环部分和轭部分，所述轴环部分和所述轭部由具有芯吸整理剂的四向弹性织物制成; 一对下套筒部分，每个所述下套筒部分由非吸湿疏水织物制成; 和可选的一对腋下部分，每个所述腋下部分由编织的抗菌织物制成。

    Growth arrest homebox gene
    9.
    再颁专利
    Growth arrest homebox gene 有权
    生长抑制家箱基因

    公开(公告)号：USRE39219E1

    公开(公告)日：2006-08-01

    申请号：US09755320

    申请日：2001-01-05

    申请人： David H. Gorski ,  Kenneth Walsh

    发明人： David H. Gorski ,  Kenneth Walsh

    IPC分类号： C12N15/12 ,  C12N15/63 ,  C12N1/21 ,  C12N5/10

    CPC分类号： C07K14/4703 ,  A61K38/00

    摘要： A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

    摘要翻译： 已经发现了一种新的生长停滞同源盒基因，并且已经在大鼠和人中确定了核苷酸序列。 新型同源盒基因的表达抑制血管平滑肌细胞生长。 生长停滞同源盒基因以下简称为“Gax基因”及其相应的蛋白质可用于血管平滑肌细胞增殖的研究，以及由过度平滑肌细胞增殖引起的血管疾病的治疗，特别是球囊血管成形术 。