再颁专利
- 专利标题： Heterobifunctional pan-selectin inhibitors
- 专利标题（中）： 异双功能泛选择素抑制剂
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申请号： US13484020申请日： 2012-05-30
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公开(公告)号： USRE44778E1公开(公告)日： 2014-02-25
- 发明人: John L. Magnani , John T. Patton, Jr. , Arun K. Sarkar , Sergei A. Svarovsky , Beat Ernst
- 申请人： John L. Magnani , John T. Patton, Jr. , Arun K. Sarkar , Sergei A. Svarovsky , Beat Ernst
- 申请人地址： US MD Gaithersburg
- 专利权人： Glycomimetics, Inc.
- 当前专利权人： Glycomimetics, Inc.
- 当前专利权人地址： US MD Gaithersburg
- 代理机构： Ropes & Gray LLP
- 主分类号： C07H15/22
- IPC分类号： C07H15/22
摘要：
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).
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