Invention Application
- Patent Title: MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
- Patent Title (中): ATP结合蛋白转运蛋白的调节剂
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Application No.: PCT/US2004029206Application Date: 2004-09-07
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Publication No.: WO2005026137A3Publication Date: 2005-07-21
- Inventor: MILLER MARK T , HADIDA RUAH SARA S , SINGH ASHAVINI K , CLEVELAND THOMAS , MAKINGS LEWIS R , HAMILTON MATTHEW , GROOTENHUIS PETER D J
- Applicant: VERTEX PHARMA , MILLER MARK T , HADIDA RUAH SARA S , SINGH ASHAVINI K , CLEVELAND THOMAS , MAKINGS LEWIS R , HAMILTON MATTHEW , GROOTENHUIS PETER D J
- Assignee: VERTEX PHARMA,MILLER MARK T,HADIDA RUAH SARA S,SINGH ASHAVINI K,CLEVELAND THOMAS,MAKINGS LEWIS R,HAMILTON MATTHEW,GROOTENHUIS PETER D J
- Current Assignee: VERTEX PHARMA,MILLER MARK T,HADIDA RUAH SARA S,SINGH ASHAVINI K,CLEVELAND THOMAS,MAKINGS LEWIS R,HAMILTON MATTHEW,GROOTENHUIS PETER D J
- Priority: US50044403 2003-09-06
- Main IPC: A61K31/426
- IPC: A61K31/426 ; A61K31/427 ; A61P43/00 ; C07D263/48 ; C07D277/46 ; C07D277/82 ; C07D417/02 ; C07D417/04 ; C07D417/06 ; C07D417/12
Abstract:
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including CF Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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