发明申请
WO2008089257A2 DRUG ELUTING MEDICAL DEVICE USING POLYMERIC THERAPEUTICS WITH TRANSGLUTAMINASE SUBSTRATES
审中-公开
使用聚氨酯酶底物的聚合物治疗药物给药医疗器械
- 专利标题： DRUG ELUTING MEDICAL DEVICE USING POLYMERIC THERAPEUTICS WITH TRANSGLUTAMINASE SUBSTRATES
- 专利标题（中）： 使用聚氨酯酶底物的聚合物治疗药物给药医疗器械
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申请号： PCT/US2008051195申请日： 2008-01-16
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公开(公告)号： WO2008089257A2公开(公告)日： 2008-07-24
- 发明人: RANADE SHRIRANG , STECKEL MARK , OHRI RACHIT
- 申请人： CAPPELLA INC , RANADE SHRIRANG , STECKEL MARK , OHRI RACHIT
- 专利权人： CAPPELLA INC,RANADE SHRIRANG,STECKEL MARK,OHRI RACHIT
- 当前专利权人： CAPPELLA INC,RANADE SHRIRANG,STECKEL MARK,OHRI RACHIT
- 优先权： US88510507 2007-01-16; US88509707 2007-01-16; US88510907 2007-01-16; US88511207 2007-01-16; US94230107 2007-06-06; US94230907 2007-06-06; US94307707 2007-06-11
- 主分类号： A61K47/48
- IPC分类号： A61K47/48
摘要：
Disclosed herein are coatings for implantable medical device. The coatings comprise a composition, comprising a polymer linked to a chemical moiety through a covalent bond, wherein the chemical moiety forms a pharmaceutically active agent upon degradation (e.g., hydrolysis) of the covalent bond; and transglutaminase substrates.
