发明申请
WO2009148245A2 NOVEL NIACIN AND HMG-COA REDUCTASE INHIBITOR COMBINATION FORMULATION
审中-公开
新型氨基酸和HMG-COA还原抑制剂组合制剂
- 专利标题： NOVEL NIACIN AND HMG-COA REDUCTASE INHIBITOR COMBINATION FORMULATION
- 专利标题（中）： 新型氨基酸和HMG-COA还原抑制剂组合制剂
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申请号： PCT/KR2009002923申请日： 2009-06-02
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公开(公告)号： WO2009148245A2公开(公告)日： 2009-12-10
- 发明人: CHOI YOUN-WOONG , MIN BYUNG-GU , CHO SANG-MIN , KIM JONG-IL , KIM DAE-WOOK , JEONG YONG-MI , JANG JAE-SANG , RYOO BYUNG-HWAN
- 申请人： SEOUL PHARMA CO LTD , CHOI YOUN-WOONG , MIN BYUNG-GU , CHO SANG-MIN , KIM JONG-IL , KIM DAE-WOOK , JEONG YONG-MI , JANG JAE-SANG , RYOO BYUNG-HWAN
- 专利权人： SEOUL PHARMA CO LTD,CHOI YOUN-WOONG,MIN BYUNG-GU,CHO SANG-MIN,KIM JONG-IL,KIM DAE-WOOK,JEONG YONG-MI,JANG JAE-SANG,RYOO BYUNG-HWAN
- 当前专利权人： SEOUL PHARMA CO LTD,CHOI YOUN-WOONG,MIN BYUNG-GU,CHO SANG-MIN,KIM JONG-IL,KIM DAE-WOOK,JEONG YONG-MI,JANG JAE-SANG,RYOO BYUNG-HWAN
- 优先权： KR20080051873 2008-06-02
- 主分类号： A61K9/22
- IPC分类号： A61K9/22
摘要：
The present invention relates to a controlled release formulation containing niacin. More specifically, the present invention relates to a controlled release-niacin formulation and a preparation method thereof, wherein the controlled release-niacin formulation comprises niacin, hydroxypropyl methylcellulose, carboxyvinyl polymers, additives, disintegrants, and lubricants, wherein the carboxyvinyl polymer and hydroxypropyl methylcellulose are included so that the weight ratio of the carboxyvinyl polymer: HPMC is 1:1 - 1:100. In addition, the present invention provides a combination formulation further containing an HMG-CoA reductase inhibitor in the controlled release-niacin formulation and a preparation method thereof.
公开/授权文献
