Invention Application
- Patent Title: HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
- Patent Title (中): 异氟烷化合物有效用作RAF激酶抑制剂
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Application No.: PCT/US2009/069795Application Date: 2009-12-30
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Publication No.: WO2010078408A1Publication Date: 2010-07-08
- Inventor: CHUAQUI, Claudio , COSSROW, Jennifer , DOWLING, James , GUAN, Bing , HOEMANN, Michael , ISHCHENKO, Alexey , JONES, John, Howard , KABIGTING, Lori , KUMARAVEL, Gnanasambandam , PENG, Hairuo , POWELL, Noel , RAIMUNDO, Brian , TANAKA, Hiroko , VAN VLOTEN, Kurt , VESSELS, Jeffrey , XIN, Zhili
- Applicant: BIOGEN IDEC MA INC. , SUNESIS PHARMACEUTICALS, INC. , CHUAQUI, Claudio , COSSROW, Jennifer , DOWLING, James , GUAN, Bing , HOEMANN, Michael , ISHCHENKO, Alexey , JONES, John, Howard , KABIGTING, Lori , KUMARAVEL, Gnanasambandam , PENG, Hairuo , POWELL, Noel , RAIMUNDO, Brian , TANAKA, Hiroko , VAN VLOTEN, Kurt , VESSELS, Jeffrey , XIN, Zhili
- Applicant Address: 14 Cambridge Center Cambridge, MA 02142 US
- Assignee: BIOGEN IDEC MA INC.,SUNESIS PHARMACEUTICALS, INC.,CHUAQUI, Claudio,COSSROW, Jennifer,DOWLING, James,GUAN, Bing,HOEMANN, Michael,ISHCHENKO, Alexey,JONES, John, Howard,KABIGTING, Lori,KUMARAVEL, Gnanasambandam,PENG, Hairuo,POWELL, Noel,RAIMUNDO, Brian,TANAKA, Hiroko,VAN VLOTEN, Kurt,VESSELS, Jeffrey,XIN, Zhili
- Current Assignee: BIOGEN IDEC MA INC.,SUNESIS PHARMACEUTICALS, INC.,CHUAQUI, Claudio,COSSROW, Jennifer,DOWLING, James,GUAN, Bing,HOEMANN, Michael,ISHCHENKO, Alexey,JONES, John, Howard,KABIGTING, Lori,KUMARAVEL, Gnanasambandam,PENG, Hairuo,POWELL, Noel,RAIMUNDO, Brian,TANAKA, Hiroko,VAN VLOTEN, Kurt,VESSELS, Jeffrey,XIN, Zhili
- Current Assignee Address: 14 Cambridge Center Cambridge, MA 02142 US
- Agency: ROBIDOUX, Andrea, L.C.
- Priority: US61/141,561 20081230
- Main IPC: C07D261/08
- IPC: C07D261/08 ; C07D409/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D487/04 ; C07D413/12 ; A61K31/416 ; A61P35/00 ; C07D513/04 ; A61K31/437 ; A61K31/422 ; A61K31/428 ; A61K31/429
Abstract:
The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf -mediated diseases.
Information query
