发明申请
WO2011086570A1 PROCESS FOR PREPARATION OF CYANOALKYLPROPIONATE DERIVATIVES 审中-公开
制备氰基丙烯酸酯衍生物的方法

PROCESS FOR PREPARATION OF CYANOALKYLPROPIONATE DERIVATIVES
摘要:
A process for preparation of the compound (I) and salts thereof is provided. The process comprises reacting an alkali cyanide and paraformaldehyde to form a slurry of glycolonitrile followed by neutralizing, mixing the neutralized slurry containing glycolonitrile with an alkali ethoxide and an cyanoacetate to obtain the alkali salt of compound (I), and neutralizing the alkali salt of compound (I) to obtain the compound (I), wherein R represents a straight or branched chain alkyl having C 1 -C 18 carbon atoms.
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