Invention Application
WO2011136506A3 METHOD FOR PRODUCING RECOMBINANT COMPLEX ANTIGENS USING NANOPARTICLES OF HUMAN ROTAVIRUS
审中-公开
使用人轮状病毒纳米颗粒生产重组复合抗原的方法
- Patent Title: METHOD FOR PRODUCING RECOMBINANT COMPLEX ANTIGENS USING NANOPARTICLES OF HUMAN ROTAVIRUS
- Patent Title (中): 使用人轮状病毒纳米颗粒生产重组复合抗原的方法
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Application No.: PCT/KR2011002937Application Date: 2011-04-22
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Publication No.: WO2011136506A3Publication Date: 2012-04-19
- Inventor: KIM WON YONG , CHUNG IN SIK , KIM JONG-BUM , SHON DONG-HWA , THAN VAN THAI , YOON JANG WON , PARK JOO HYOUNG , BAEK IN-HYUK
- Applicant: UNIV CHUNG ANG IND , KIM WON YONG , CHUNG IN SIK , KIM JONG-BUM , SHON DONG-HWA , THAN VAN THAI , YOON JANG WON , PARK JOO HYOUNG , BAEK IN-HYUK
- Assignee: UNIV CHUNG ANG IND,KIM WON YONG,CHUNG IN SIK,KIM JONG-BUM,SHON DONG-HWA,THAN VAN THAI,YOON JANG WON,PARK JOO HYOUNG,BAEK IN-HYUK
- Current Assignee: UNIV CHUNG ANG IND,KIM WON YONG,CHUNG IN SIK,KIM JONG-BUM,SHON DONG-HWA,THAN VAN THAI,YOON JANG WON,PARK JOO HYOUNG,BAEK IN-HYUK
- Priority: KR20100041095 2010-04-30
- Main IPC: C12N15/46
- IPC: C12N15/46 ; C07K19/00 ; C12N15/51 ; C12N15/866
Abstract:
The present invention relates to a construct for expressing rotavirus complex antigens having heterologous virus antigen epitopes, to a vaccine composition comprising the rotavirus complex antigens, to rotavirus-like particles comprising the rotavirus complex antigens, and to a vaccine composition comprising the rotavirus-like particles. According to the present invention, complex antigens comprising both the rotavirus antigens and epitopes of heterologous viruses different from the rotaviruses, and rotavirus-like particles comprising the complex antigens can be mass-produced at low costs. The method of the present invention can be applied to the study and development of novel complex vaccines against rotaviruses and heterologous viruses.
Public/Granted literature
- WO2011136506A9 METHOD FOR PRODUCING RECOMBINANT COMPLEX ANTIGENS USING NANOPARTICLES OF HUMAN ROTAVIRUS Public/Granted day:2012-03-01
Information query
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