发明申请
- 专利标题: ANTI-ERBB3 ANTIBODIES
- 专利标题(中): 抗ERBB3抗体
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申请号: PCT/US2011031829申请日: 2011-04-08
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公开(公告)号: WO2011136911A3公开(公告)日: 2012-03-08
- 发明人: VINCENT SYLVIE , WINSTON WILLIAM M JR , WANG FANG , WEILER SOLLY , MEETZE KRISTAN , BREAULT LYNE , BOTEGA STEVE , CHEN TING , DEPRIMA MICHAEL , FLEET CHRISTINA , TYLER STEVEN , WOO JIN-KYEUNG , GYURIS JENO
- 申请人: AVEO PHARMACEUTICALS INC , VINCENT SYLVIE , WINSTON WILLIAM M JR , WANG FANG , WEILER SOLLY , MEETZE KRISTAN , BREAULT LYNE , BOTEGA STEVE , CHEN TING , DEPRIMA MICHAEL , FLEET CHRISTINA , TYLER STEVEN , WOO JIN-KYEUNG , GYURIS JENO
- 专利权人: AVEO PHARMACEUTICALS INC,VINCENT SYLVIE,WINSTON WILLIAM M JR,WANG FANG,WEILER SOLLY,MEETZE KRISTAN,BREAULT LYNE,BOTEGA STEVE,CHEN TING,DEPRIMA MICHAEL,FLEET CHRISTINA,TYLER STEVEN,WOO JIN-KYEUNG,GYURIS JENO
- 当前专利权人: AVEO PHARMACEUTICALS INC,VINCENT SYLVIE,WINSTON WILLIAM M JR,WANG FANG,WEILER SOLLY,MEETZE KRISTAN,BREAULT LYNE,BOTEGA STEVE,CHEN TING,DEPRIMA MICHAEL,FLEET CHRISTINA,TYLER STEVEN,WOO JIN-KYEUNG,GYURIS JENO
- 优先权: US32271210 2010-04-09
- 主分类号: C07K16/32
- IPC分类号: C07K16/32 ; A61K39/395 ; A61P35/00 ; C12N15/13
摘要:
Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB 3/HER3.