发明申请
- 专利标题： CHEMICAL COMPOUNDS
- 专利标题（中）： 化学化合物
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申请号： PCT/IB2011/052998申请日： 2011-07-06
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公开(公告)号： WO2012007877A2公开(公告)日： 2012-01-19
- 发明人: BELL, Andrew Simon , BROWN, Alan Daniel , LEWTHWAITE, Russell Andrew , PEREZ PACHECO, Manuel , RAWSON, David James , STORER, Robert Ian , SWAIN, Nigel Alan
- 申请人： PFIZER LIMITED , BELL, Andrew Simon , BROWN, Alan Daniel , LEWTHWAITE, Russell Andrew , PEREZ PACHECO, Manuel , RAWSON, David James , STORER, Robert Ian , SWAIN, Nigel Alan
- 申请人地址： Ramsgate Road Sandwich Kent CT13 9NJ GB
- 专利权人： PFIZER LIMITED,BELL, Andrew Simon,BROWN, Alan Daniel,LEWTHWAITE, Russell Andrew,PEREZ PACHECO, Manuel,RAWSON, David James,STORER, Robert Ian,SWAIN, Nigel Alan
- 当前专利权人： PFIZER LIMITED,BELL, Andrew Simon,BROWN, Alan Daniel,LEWTHWAITE, Russell Andrew,PEREZ PACHECO, Manuel,RAWSON, David James,STORER, Robert Ian,SWAIN, Nigel Alan
- 当前专利权人地址： Ramsgate Road Sandwich Kent CT13 9NJ GB
- 优先权： US61/491,540 20110531; US61/363,421 20100712
- 主分类号： C07D213/64
- IPC分类号： C07D213/64
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula 10 (I): (I) or a pharmaceutically acceptable salt thereof, wherein Z, R 1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
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