发明申请
- 专利标题： FUNCTIONALIZED CYANINE DYES
- 专利标题（中）： 功能性氰基染料
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申请号： PCT/US2011/049242申请日： 2011-08-25
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公开(公告)号： WO2012027618A2公开(公告)日： 2012-03-01
- 发明人: SHEN, Gene , YUE, Stephen
- 申请人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , SHEN, Gene , YUE, Stephen
- 申请人地址： 1380 Willow Road Menlo Park, CA 94025 US
- 专利权人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC.,SHEN, Gene,YUE, Stephen
- 当前专利权人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC.,SHEN, Gene,YUE, Stephen
- 当前专利权人地址： 1380 Willow Road Menlo Park, CA 94025 US
- 代理机构： MANN, Jeffry, S. et al.
- 优先权： US61/377,022 20100825; US61/377,038 20100825; US61/377,004 20100825; US61/377,048 20100825; US61/377,031 20100825
- 主分类号： C07D403/06
- IPC分类号： C07D403/06 ; C07D209/10 ; C07D209/18 ; C07D209/30 ; C09B23/00
摘要：
The invention provides a novel class of cyanine dyes that are functionalized with a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.
