发明申请
- 专利标题： NON-ANTICOAGULANT SULFATED OR SULFONATED POLYSACCHARIDES
- 专利标题（中）： 非抗血清磺化或磺化多糖
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申请号： PCT/US2013/023892申请日： 2013-01-30
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公开(公告)号： WO2013116366A1公开(公告)日： 2013-08-08
- 发明人: DOCKAL, Michael , SCHEIFLINGER, Fritz , KNAPPE, Sabine , TILL, Susanne , HAI, Ton , SANDERS, Paul , DANDE, Prasad , JIANG, Cong
- 申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , DOCKAL, Michael , SCHEIFLINGER, Fritz , KNAPPE, Sabine , TILL, Susanne , HAI, Ton , SANDERS, Paul , DANDE, Prasad , JIANG, Cong
- 申请人地址： One Baxter Parkway Deerfield, IL 60015 US
- 专利权人： BAXTER INTERNATIONAL INC.,BAXTER HEALTHCARE S.A.,DOCKAL, Michael,SCHEIFLINGER, Fritz,KNAPPE, Sabine,TILL, Susanne,HAI, Ton,SANDERS, Paul,DANDE, Prasad,JIANG, Cong
- 当前专利权人： BAXTER INTERNATIONAL INC.,BAXTER HEALTHCARE S.A.,DOCKAL, Michael,SCHEIFLINGER, Fritz,KNAPPE, Sabine,TILL, Susanne,HAI, Ton,SANDERS, Paul,DANDE, Prasad,JIANG, Cong
- 当前专利权人地址： One Baxter Parkway Deerfield, IL 60015 US
- 代理机构： MANN, Jeffry, S.
- 优先权： US61/592,549 20120130
- 主分类号： A61K31/715
- IPC分类号： A61K31/715 ; A61P7/04
摘要：
The present invention provides non-anticoagulant sulfated or sulfonated polysaccharides (NASPs), which accelerate the blood clotting process. Also provided are pharmaceutical formulations comprising a NASP of the invention in conjunction with a pharmaceutically acceptable excipient and, in various embodiments, these formulations are unit dosage formulations. The invention provides a NASP formulation, which is orally bioavailable. Also provided are methods for utilizing the compounds and formulations of the invention to promote blood clotting in vivo as therapeutic and prophylactic agents and in vitro as an aid to studies of the blood clotting process.
