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    PATIENT INFORMATION SOFTWARE SYSTEM INCLUDING INFUSION MAP
    2.
    发明申请
    PATIENT INFORMATION SOFTWARE SYSTEM INCLUDING INFUSION MAP 审中-公开
    患者信息软件系统，包括输注图

    公开(公告)号：WO2014039835A1

    公开(公告)日：2014-03-13

    申请号：PCT/US2013/058532

    申请日：2013-09-06

    Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A.

    Inventor： DUDAR, Thomas Edward ,  JEPSON, Steven Clarence

    IPC: G06F19/00

    CPC classification number: G06F19/3468 ,  G06F19/00 ,  G16H40/63

    Abstract: An infusion map system [10] includes a memory [14] storing at least infusion mapping instructions, and a processor [16] that executes the stored instructions. When the processor [16] executes the infusion mapping instructions, the infusion map system [10] performs a displaying function that displays at least a portion of an electronic medical record [30, 32, 34] associated with a patient and a diagramming function that receives the electronic medical record and generates an infusion map [38] showing all intravenous drugs being administered to the patient. For each of the drugs, the infusion map [38] further illustrates a route of administration for the drug. An order administering function performed by the system [10] allows a user to alter the infusion map [38], and a record updating function of annotating the electronic medical record to correspond to the altered infusion map.

    Abstract translation: 输注图谱系统[10]包括存储至少输注映射指令的存储器[14]和执行存储的指令的处理器[16]。 当处理器[16]执行输注映射指令时，输注图系统[10]执行显示功能，其显示与患者相关联的电子医疗记录[30,32,34]的至少一部分和图示功能， 接收电子医疗记录并产生显示给患者的所有静脉内药物的输注图[38]。 对于每种药物，输注图[38]进一步说明了药物的给药途径。 由系统[10]执行的订单管理功能允许用户改变输注图[38]，以及注册电子病历的记录更新功能以对应于改变的输注图。

    SYRINGE STORAGE TRAY
    3.
    发明申请
    SYRINGE STORAGE TRAY 审中-公开
    SYRINGE存储托盘

    公开(公告)号：WO2013176703A1

    公开(公告)日：2013-11-28

    申请号：PCT/US2012/070804

    申请日：2012-12-20

    Applicant: BAXTER INTERNATIONAL, INC. ,  BAXTER HEALTHCARE S.A.

    Inventor： HEAD, Brian, R. ,  COHEN, Amy, R. ,  BERTOS, Georgios ,  WEHRLI, Michael, P. ,  YARDIMCI, Atif, M. ,  MOORE, Joseph, S. ,  WILLIAMSON, Mark, E.

    IPC: A61M5/00

    CPC classification number: A61M5/002 ,  A61M5/008 ,  A61M5/31501 ,  A61M2005/3104 ,  B01F11/0005

    Abstract: A storage tray (10) for one or more syringes is provided that comprises a recess (32) for each of the syringes to be held in the tray. Each recess has first and second opposed sidewalls (34, 36) that define a space therebetween for receiving the barrel of the syringe. Each of the first and second sidewalls has one or more deformable projections (40) thereon that protrude into the space between the sidewalls for positively retaining the barrel of the syringe between the first and second sidewalls. Additionally, a slot (50) is provided for receiving the thumb rest (16) of the plunger (14), with the slot comprising a third sidewall (52) oriented generally transverse to the first and second sidewalls, with the third sidewall including a further projection (54) for engaging a surface of the thumb rest.

    Abstract translation: 提供了一种用于一个或多个注射器的储存托盘（10），其包括用于待保持在托盘中的每个注射器的凹部（32）。 每个凹部具有第一和第二相对的侧壁（34,36），其在其间限定用于接收注射器的筒体的空间。 第一和第二侧壁中的每一个在其上具有突出到侧壁之间的空间中的一个或多个可变形突起（40），用于将注射器的筒体保持在第一和第二侧壁之间。 另外，设置有用于接收柱塞（14）的拇指托架（16）的槽（50），其中所述槽包括大致横向于第一和第二侧壁定向的第三侧壁（52），其中第三侧壁包括 用于接合拇指托的表面的另外的突出部（54）。

    PHARMACEUTICAL COMPOSITION COMPRISING CD34+ CELLS
    4.
    发明申请
    PHARMACEUTICAL COMPOSITION COMPRISING CD34+ CELLS 审中-公开
    包含CD34 +细胞的药物组合物

    公开(公告)号：WO2013126590A2

    公开(公告)日：2013-08-29

    申请号：PCT/US2013/027163

    申请日：2013-02-21

    Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A.

    Inventor： PALMER, Lora ,  MOTLAGH, Delara ,  COHEN, Amy ,  PALMER, Lora ,  AMRANI, David L.

    IPC: A61K35/14

    CPC classification number: A61K35/14 ,  A61K9/0019 ,  A61K35/12 ,  A61K35/15 ,  A61K47/12 ,  A61K47/42 ,  A61K2035/124

    Abstract: The invention relates to the field of treatment of ischemic conditions and diseases using a cell population comprising CD34+ cells isolated from peripheral blood of a subject. The invention provides a pharmaceutical composition comprising (i) a cell population comprising CD34+ cells, (ii) a plasma protein, and (iii) an isotonic solution comprising at least one salt, said isotonic solution comprising acetate, gluconate, or both acetate and gluconate. Methods of treating tissue damaged by ischemia in a subject and methods of treating a medical condition, wherein the pharmaceutical composition of the invention is administered, are further provided herein. Also, methods of promoting mobilization of CD34+ cells from bone marrow into peripheral blood are provided herein.

    Abstract translation: 本发明涉及使用包含从受试者的外周血分离的CD34 +细胞的细胞群的缺血性病症和疾病的治疗领域。 本发明提供一种药物组合物，其包含（i）包含CD34 +细胞的细胞群，（ii）血浆蛋白，和（iii）包含至少一种盐的等渗溶液，所述等渗溶液包含乙酸盐，葡萄糖酸盐或乙酸盐和葡萄糖酸盐 。 在本文中进一步提供了治疗受试者局部损伤的组织的方法和治疗其中施用本发明的药物组合物的医疗状况的方法。 此外，本文提供了促进CD34 +细胞从骨髓中移动到外周血中的方法。

    METHOD FOR THE PRODUCTION OF A POLYMERIZED PRODUCT
    9.
    发明申请
    METHOD FOR THE PRODUCTION OF A POLYMERIZED PRODUCT 审中-公开
    生产聚合物的方法

    公开(公告)号：WO2012171983A2

    公开(公告)日：2012-12-20

    申请号：PCT/EP2012/061253

    申请日：2012-06-14

    Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  DELMOTTE, Yves

    Inventor： DELMOTTE, Yves

    CPC classification number: C12P21/00 ,  B01F13/0071 ,  C07K1/02 ,  C07K14/75 ,  C07K14/765 ,  C07K14/78 ,  C08L5/04 ,  C08L5/08 ,  C08L89/00 ,  C08L89/06 ,  C12N9/54

    Abstract: The invention discloses a method for the production of a polymerized product comprising the following steps: - providing a polymerization device to which a polymerization mixture and a separation medium can be applied and wherein flow of said mixture and medium can be conducted in appropriate ducts for said mixture and medium, - transporting said polymerization mixture in a duct of said polymerization device thereby allowing the polymerization reaction, - transporting said mixture in a duct of said polymerization device in a continuous flow, - interrupting said continuous flow of said mixture with said separation medium so as to obtain consecutive volumes of said mixture and volumes of said separation medium, - further transporting said consecutive volumes of said mixture and volumes of said separation medium in a duct of said polymerization device wherein said mixture further polymerizes to obtain a discontinuous polymerized product, and removing said discontinuous polymerized product from said polymerization device.

    Abstract translation: 本发明公开了一种生产聚合产物的方法，包括以下步骤： - 提供聚合装置，聚合混合物和分离介质可以被施加到聚合装置上，并且所述混合物和介质的流动可以在适当的管道中进行，用于所述 混合物和介质， - 将所述聚合混合物输送在所述聚合装置的管道中，从而允许聚合反应，以连续流动方式在所述聚合装置的管道中输送所述混合物， - 用所述分离介质中断所述混合物的所述连续流动 以便获得所述分离介质的所述混合物和体积的连续体积， - 在所述聚合装置的管道中进一步输送所述连续体积的所述分离介质的所述混合物和体积，其中所述混合物进一步聚合以获得不连续的聚合产物， 并除去所述不连续聚合产物 从所述聚合装置。

    METHODS FOR ISOLATING AND QUANTIFYING ANTIGEN FROM VACCINES
    10.
    发明申请
    METHODS FOR ISOLATING AND QUANTIFYING ANTIGEN FROM VACCINES 审中-公开
    从疫苗中分离和定量抗原的方法

    公开(公告)号：WO2012145386A1

    公开(公告)日：2012-10-26

    申请号：PCT/US2012/034054

    申请日：2012-04-18

    Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE S.A. ,  GRANINGER, Michael ,  KALIWODA, Martin

    Inventor： GRANINGER, Michael ,  KALIWODA, Martin

    IPC: C07K14/005 ,  C12N7/00 ,  G01N33/68

    CPC classification number: C07K14/005 ,  C12N7/00 ,  C12N2760/16051 ,  C12N2760/16151

    Abstract: The disclosure relates to the development of improved methods for quantifying antigen in a vaccine composition in the absence of available antigen standards. More specifically, the disclosure provides fast and robust methods of separating antigens from vaccine compositions, comprising the steps of solubilizing antigen without detergent and without alkylation, using acidification to prevent antigen subtypes from binding again, isolating antigen subtypes with chromatography, and quantifiying the eluted antigen with amino acid analysis. The methods of the disclosure are applicable for use with a variety of antigens, thereby providing an improved method in the art of vaccine manufacturing to date.

    Abstract translation: 本公开涉及在没有可用抗原标准的情况下开发用于在疫苗组合物中定量抗原的改进方法。 更具体地，本公开提供了从疫苗组合物中分离抗原的快速和有效的方法，包括以下步骤：使用酸化增溶抗原而不用洗涤剂而不进行烷基化，以防止抗原亚型再次结合，用色谱法分离抗原亚型，并定量洗脱的抗原 用氨基酸分析。 本公开的方法适用于各种抗原，从而提供迄今为止疫苗制造领域的改进方法。

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