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公开(公告)号：WO2023081681A1
公开(公告)日：2023-05-11
申请号：PCT/US2022/079115
申请日：2022-11-02
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： FOLEY, John Devlin
Abstract: Disclosed herein are nitric oxide donors and methods of use thereof.
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公开(公告)号：WO2023070035A1
公开(公告)日：2023-04-27
申请号：PCT/US2022/078433
申请日：2022-10-20
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： JANSSON, Olof
Abstract: A peritoneal dialysis system comprises a cycler including a peristaltic pump actuator, and a weigh scale; a disposable set including a peristaltic pump tube operable with the peristaltic pump actuator, a patient line in fluid communication with the peristaltic pump tube, and a heating container in operable communication with the weigh scale; and a control unit configured to cause (i) the peristaltic pump actuator to operate at a rotational speed to cause an amount of fluid to enter the heating container, (ii) weigh the amount of fluid, and (iii) determine at least one of a mass rate or volume rate for the rotational speed.
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公开(公告)号：WO2023043621A1
公开(公告)日：2023-03-23
申请号：PCT/US2022/042202
申请日：2022-08-31
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： KRISHNAN, Lalu NMI
Abstract: A dialysis system with an integrated adaptive virtual assistant and/or chatbot is disclosed. In an example, logic for the adaptive virtual assistant and/or chatbot may be integrated with a dialysis machine or provided remotely in a cloud computing environment. The adaptive virtual assistant and/or chatbot is configured to use speech or text from a patient in conjunction with medical information from the dialysis machine to determine an issue a patient is experiencing or a probability that a patient will experience (or is experiencing) a medical complication. For an issue, the adaptive virtual assistant and/or chatbot is configured to provide a resolution, which may include a recommended action for a patient or a clinician to perform. The use of the medical information enables the adaptive virtual assistant and/or chatbot to more quickly converge upon a solution without needing to ask a patient numerous questions.
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公开(公告)号：WO2023038886A1
公开(公告)日：2023-03-16
申请号：PCT/US2022/042613
申请日：2022-09-06
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
IPC: A61M1/16 , F24H1/10 , F24H15/128
Abstract: An inline heating system (10) including an inline heater (20) including a heater element (26a, 26b); a control unit (50) configured to cause one of voltage or current to be applied to power the inline heater; and a current or voltage meter (66, 66a, 66b) positioned and arranged to measure the other of current or voltage at the heater element due to the applied voltage or current, wherein the control unit is further configured to determine a heater element resistance using the applied voltage or current and the measured current or voltage as part of a no flow or low flow condition detection algorithm implemented by the control unit, wherein the voltage or current applied to power the inline heater is stopped if the no flow or low flow condition is detected.
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公开(公告)号：WO2022260904A1
公开(公告)日：2022-12-15
申请号：PCT/US2022/031775
申请日：2022-06-01
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： RAMKUMAR, Jeyachandran , WELLINGS, Anders J.
IPC: A61M1/28
Abstract: A peritoneal dialysis ("PD") machine includes a water pump; a concentrate pump; a water valve, and an inlet to the water valve positioned to receive purified water; a concentrate valve, and an inlet to the concentrate valve positioned to receive PD fluid concentrate; a mixing line located downstream from the water pump and the a concentrate pump; a conductivity sensor positioned to sense mixed purified water and PD fluid concentrate that form fresh PD fluid; a flexible patient line configured to bring fresh PD fluid to and remove used PD fluid from a patient; and a control unit configured to control the water pump, the concentrate pump, the water valve and the concentrate valve, to receive an output from the conductivity sensor, and to run a disinfection sequence in which (i) the inlet to the concentrate valve alternatively receives disinfectant or (ii) the flexible patient line alternatively receives disinfectant.
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Patent Agency Ranking
公开(公告)号：WO2022251106A1
公开(公告)日：2022-12-01
申请号：PCT/US2022/030517
申请日：2022-05-23
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： BOUREZG, Zouaoui , DUPONT, Caroline Roselyne , DESBROSSES, Freddy , COUTHOUIS, Aurélie , BROSSARD, Gabriel , PADULA, Pierpaolo , TROUILLY, Jean-Luc
IPC: A23L33/00 , A23L33/115 , A23L33/125 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/175 , B65D81/32 , A61J1/20
Abstract: The present disclosure relates to a terminally heat-sterilized ready-to-use parenteral nutrition formulation comprising all macronutrients and micronutrients required to meet the clinical guidelines for parenteral nutrition, wherein all said micronutrients and macronutrients are provided in one multi-chamber bag (MCB). The disclosure is also directed to a parenteral nutrition formulation comprising all such macronutrients and micronutrients. More specifically, the present disclosure is directed to a MCB comprising at least five chambers containing a carbohydrate formulation in a first chamber, an amino acid formulation in a second chamber, a lipid formulation in a third chamber, a fourth chamber comprising a vitamin formulation and a fifth chamber comprising a trace element formulation, wherein the carbohydrate formulation, amino acid formulation and/or the lipid formulation may also contain certain vitamins and certain trace elements that can be stably accommodated therein.
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公开(公告)号：WO2022236053A1
公开(公告)日：2022-11-10
申请号：PCT/US2022/028070
申请日：2022-05-06
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： HORNSBY, Jack Alexander , HO, Lewis Siu Tai
IPC: A61M1/28
Abstract: An automated peritoneal dialysis system (10) comprising: a dialysis fluid pump actuator (60); a dialysis fluid carrying set (120) including a flexible sheet (136); a temperature sensor (38) positioned and arranged to sense a temperature of the dialysis fluid flowing through the dialysis fluid carrying set (120); a pressure sensor (36a, 36b) positioned and arranged to contact the flexible sheet (136) when the dialysis fluid carrying set (120) is loaded for operation with the dialysis fluid pump actuator (60); and a control unit (50) configured to (i) precondition the flexible sheet (136) for operation with the pressure sensor (36a, 36b) by causing the dialysis fluid pump actuator (60) to apply pressure to the flexible sheet (136) and (ii) use an output from the temperature sensor (38) in a compensation algorithm that modifies an output from the pressure sensor (36a, 36b).
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公开(公告)号：WO2022236051A2
公开(公告)日：2022-11-10
申请号：PCT/US2022/028067
申请日：2022-05-06
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： HORNSBY, Jack Alexander , HO, Lewis Siu Tai , MALORNI, Sergio , COOKE, Jonathon Paul , AHUJA, Akshaya , PREDA, Emil
IPC: A61M1/28 , A61M1/154 , A61M1/155 , A61M1/1565 , A61M1/159 , A61M1/1601 , A61M1/166 , A61M1/281 , A61M1/282 , A61M1/288 , A61M2205/12 , A61M2205/128 , A61M2205/14 , A61M2205/3331 , A61M2205/3334 , A61M2205/3344 , A61M2205/3368 , A61M2205/3386 , A61M2205/3393 , A61M2205/502
Abstract: A peritoneal dialysis system (10) comprises a cycler (20) including a pump actuator (60), a patient line valve actuator (34e), at least one supply line valve actuator (34b, 34c), and a drain line valve actuator (34a); and a disposable medical fluid cassette (130) including a pumping portion (126) configured to operate with the pump actuator (60), a patient line valve seat (132e) configured to operate with the patient line valve actuator (34e), a rigid body (138) defining a common well (146), at least one supply line valve seat (132b, 132c) located in the common well (146) and configured to operate with at least one supply line valve actuator (34b, 34c), and a drain line valve seat (132a) located in the common well (146) and configured to operate with the drain line valve actuator (34a).
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公开(公告)号：WO2022232686A1
公开(公告)日：2022-11-03
申请号：PCT/US2022/027269
申请日：2022-05-02
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： VARTIA, Christian Antero , NOGALES, Carlos Alberto Corrales , YANAGA, Joanna Rita , DEL CASTILLO, Jorge , BORGQVIST, Per-Olof , WALLENBORG, Anders , NORMAN, John Sterling , AGUILAR, Jeannette , HEDLUND, Madison Rachel , GUDANI, Caesar
Abstract: Methods, apparatuses, and systems for determining a correlation between intraperitoneal pressure ("IPP") measurements and patient intraperitoneal volume ("IPV") are disclosed. In an example, an apparatus is configured to determine a maximum fill volume of dialysate to be pumped into a peritoneal cavity of a patient. The apparatus also determines a plurality of iterations to achieve the maximum fill volume and a volume of the dialysate to be pumped for each of the iterations. For each iteration, the apparatus causes a dialysis machine to pump the dialysate to the peritoneal cavity based on the determined volume for that iteration, records IPP measurement output data from a pressure sensor, records or determines a total accumulated fill volume, and creates a data point for a personalized patient model corresponding to a correlation between the IPP measurement output data and the total accumulated fill volume.
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公开(公告)号：WO2022226022A1
公开(公告)日：2022-10-27
申请号：PCT/US2022/025477
申请日：2022-04-20
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： RANDALL, Paul , EYETAN, Chinemerem , WILKINSON, Sam
IPC: G16H50/80
Abstract: A graph database for outbreak tracking and management is disclosed. In an example, an outbreak management system includes a memory device storing instructions that define a graph database for disease outbreak tracking. The instructions specify, for a given host, that a host node is created and an episode node is connected to the host node via a 'case' link. Additionally, the instructions specify that a rule node is connected to the episode node via a 'found' link. The rule node is associated with a workflow, an assignment, and a notification, and includes at least one defined condition. If a condition is satisfied for a case, the rule node is linked to the episode node. This leakage causes the workflow to be added for the episode node, the episode node to be assigned to an individual or a team, and a notification to be generated regarding an association with the rule.
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