Invention Application
- Patent Title: CONSTRAINED TRICYCLIC SULFONAMIDES
- Patent Title (中): 受约束的三聚磺酰胺
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Application No.: PCT/US2015/019764Application Date: 2015-03-10
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Publication No.: WO2015138496A1Publication Date: 2015-09-17
- Inventor: OHLMEYER, Michael , KASTRINSKY, David
- Applicant: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Applicant Address: One Gustave L. Levy Place New York, New York 10029 US
- Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Current Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Current Assignee Address: One Gustave L. Levy Place New York, New York 10029 US
- Agency: FREDERICKS, Kellie S. et al.
- Priority: US61/951,186 20140311
- Main IPC: C07D223/26
- IPC: C07D223/26 ; A61K31/18 ; A61K31/5415 ; A61K31/55 ; C07D223/28 ; C07D223/32 ; C07C311/29 ; C07D279/36 ; A61P35/00 ; A61P3/10 ; A61P37/00 ; A61P17/10 ; A61P31/12 ; A61P33/00 ; A61P25/00
Abstract:
Tricyclic chemical modulators of protein phosphatase 2A are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced depression, inflammation, and acne. The compounds are of the following phenothiazine and dibenzoazepine compounds and similar genera:
Information query
