-
公开(公告)号：WO2021157593A1
公开(公告)日：2021-08-12
申请号：PCT/JP2021/003826
申请日：2021-02-03
Applicant: 株式会社Ｋｙｕｌｕｘ
IPC: H01L51/50 , C07D207/448 , C07D209/12 , C07D209/86 , C07D213/74 , C07D215/26 , C07D219/14 , C07D223/28 , C07D231/06 , C07D233/96 , C07D239/26 , C07D241/38 , C07D251/24 , C07D263/42 , C07D307/91 , C07D309/34 , C07D311/04 , C07D311/74 , C07D333/18 , C07D333/76 , C07D401/10 , C07D403/10 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/10 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/10 , C07D417/14 , C07D471/04 , C07D471/06 , C07D471/14 , C07D487/16 , C07D487/22 , C07D491/16 , C07D495/04 , C07D498/04 , C07D519/00 , C09K11/06
Abstract: ＰＢＨＴ値が０．７３０より大きい第１化合物と、ＥＳ１が第１化合物より小さくてΔＥＳＴが０．２０ｅＶ未満である第２化合物をともに含む発光組成物を用いた有機発光素子は耐久性に優れている。ＥＳ１は最低励起一重項エネルギー準位、ΔＥＳＴは最低励起一重項エネルギー準位と最低励起三重項エネルギー準位の差である。
-
2.发明申请PROCESS FOR THE PREPARATION AND PURIFICATION OF ESLICARBAZEPINE ACETATE AND INTERMEDIATES THEREOF 审中-公开乙酸异丁酯的制备和纯化方法及其中间体
公开(公告)号：WO2013008194A3
公开(公告)日：2013-03-14
申请号：PCT/IB2012053550
申请日：2012-07-11
Applicant: RANBAXY LAB LTD , HIRPARA KETAN , KHANDURI CHANDRA HAS , SHARMA MUKESH KUMAR
Inventor： HIRPARA KETAN , KHANDURI CHANDRA HAS , SHARMA MUKESH KUMAR
IPC: C07D223/28
CPC classification number: C07D223/28
Abstract: The present invention provides a novel process for the preparation of 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide, commonly known as oxcarbazepine, which is a medicament and a useful intermediate in the preparation of eslicarbazepine acetate. The present invention further provides a process for the preparation and purification of eslicarbazepine acetate.
Abstract translation: 本发明提供了一种制备10-氧代-10,11-二氢-5H-二苯并[b，f]吖庚因-5-甲酰胺（通常称为奥卡西平）的新方法，其为药物和有用的中间体 制备醋酸西拉西平。 本发明还提供了制备和纯化乙酸西酞西泮的方法。
-
公开(公告)号：WO2012060397A1
公开(公告)日：2012-05-10
申请号：PCT/JP2011/075244
申请日：2011-11-02
Applicant: 国立大学法人九州大学 , 日本ケミファ株式会社 , 井上和秀 , 津田誠 , 松村裕太
IPC: A61K45/00 , A61K31/135 , A61K31/138 , A61K31/15 , A61K31/335 , A61K31/343 , A61K31/451 , A61K31/4525 , A61K31/495 , A61K31/55 , A61K31/551 , A61P29/00 , C07D223/28 , C07D307/87 , C07D313/12 , C07D405/12 , C07D413/10
CPC classification number: A61K31/5513 , A61K31/135 , A61K31/138 , A61K31/15 , A61K31/335 , A61K31/343 , A61K31/451 , A61K31/4525 , A61K31/495 , A61K31/55 , A61K31/551 , C07D223/28 , C07D307/87 , C07D313/12 , C07D405/12 , C07D413/10 , C07D413/12
Abstract: パロキセチンや次の一般式（ＩＸ）で表されるジアゼピンジオン誘導体等のＰ２Ｘ ４ 受容体拮抗剤を帯状疱疹関連痛の急性期疼痛の予防又は治療剤として使用する。（式中、Ｒ １ は水素原子、炭素数１～８のアルキル基他を表し、 Ｒ ２ 及びＲ ３ は水素原子、炭素数１～８のアルキル基等を表し、 Ｒ ４ 及びＲ ５ は水素原子他を表し、 そして、Ｗは置換基を有していても良い環構成元素として窒素原子を１～４個含む５又は６員環の複素環を表す。）
Abstract translation: 作为与急性期带状疱疹相关的疼痛的预防或治疗剂，使用帕罗西汀或P2X4受体拮抗剂，例如通式（IX）所示的二氮杂二酮衍生物。 （式中，R 1表示氢原子，碳原子数1〜8的烷基等，R 2，R 3表示氢原子，碳原子数1〜8的烷基等，R 4，R 5 表示氢原子等，W表示含有1-4个氮原子的五元或六元环杂环，可以具有取代基的环的元素。）
-
4.发明申请NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME 审中-公开新型有机电致发光化合物和使用该有机电致发光化合物的有机电致发光器件
公开(公告)号：WO2011093603A1
公开(公告)日：2011-08-04
申请号：PCT/KR2011/000205
申请日：2011-01-12
Applicant: ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. , SHIN, Hyo Nim , CHO, Young Jun , KWON, Hyuck Joo , KIM, Bong Ok , KIM, Sung Min
Inventor： SHIN, Hyo Nim , CHO, Young Jun , KWON, Hyuck Joo , KIM, Bong Ok , KIM, Sung Min
IPC: C09K11/06 , C07D209/08 , C07D215/06 , C07D219/02 , C07D223/26 , C07D223/28 , C07D241/48 , C07D265/38 , C07D279/22 , C07D401/14 , C07F7/10 , H01L27/32 , H01L51/54
CPC classification number: C07D215/06 , C07D209/08 , C07D219/02 , C07D223/26 , C07D223/28 , C07D241/48 , C07D265/38 , C07D401/14 , C07F7/0816 , C09K11/06 , C09K2211/1011 , H01L51/006 , H01L51/5012 , H05B33/14
Abstract: Provided are a novel organic electroluminescent compound and an organic electroluminescent device using the same. Since the organic electroluminescent compound exhibits good luminous efficiency and excellent life property, it may be used to manufacture OLEDs having very superior operation life.
Abstract translation: 提供了一种新颖的有机电致发光化合物和使用其的有机电致发光器件。 由于有机电致发光化合物具有良好的发光效率和优异的寿命性质，因此可用于制造具有非常优异的使用寿命的OLED。
-
公开(公告)号：WO2011091131A2
公开(公告)日：2011-07-28
申请号：PCT/US2011/021852
申请日：2011-02-08
Applicant: DR. REDDY'S LABORATORIES LTD. , DR. REDDY'S LABORATORIES, INC. , KATKAM, Srinivas , SAGYAM, Rajeshwar, Reddy , BUCHIKONDA, Ravinder , MUTTAVARAPU, Murali, Mohan , MUNAGALA, Sridhar , CHIKKA, Rambabu
Inventor： KATKAM, Srinivas , SAGYAM, Rajeshwar, Reddy , BUCHIKONDA, Ravinder , MUTTAVARAPU, Murali, Mohan , MUNAGALA, Sridhar , CHIKKA, Rambabu
IPC: C07D223/24 , C07D223/28 , A61K31/55
CPC classification number: A61K31/55 , C07D223/24 , C07D223/28
Abstract: Processes for the preparation of eslicarbazepine acetate and intermediates thereof. Also provided are polymorphic forms of eslicarbazepine acetate and methods for their preparation.
Abstract translation: 制备醋酸艾塞利西平及其中间体的方法 还提供了醋酸艾利卡西平的多晶型物及其制备方法。
-
Patent Agency Ranking6.发明申请NEW DERIVATIVES OF 10,11-DIHYDRO-10-OXO-5H-DIBENZ/b,F/AZEPINE-5-CARBOXAMIDE 审中-公开10,11-二氢-10-OXO-5H-DIBENZ / b，F / AZEPINE-5-羧酰胺的新衍生物
公开(公告)号：WO1997045416A1
公开(公告)日：1997-12-04
申请号：PCT/IB1997000691
申请日：1997-05-27
Applicant: PORTELA & CA. S.A.
Inventor： PORTELA & CA. S.A. , BENES¿, Jan , SOARES DA SILVA, Patrício, Manuel, Vieira, Araujo , LEARMONTH, David, Alexander
IPC: C07D223/28
CPC classification number: C07D223/30
Abstract: Compounds of general formula (I) have valuable pharmaceutical properties especially in the treatment of some disturbances in the central and peripheral nervous system. The compounds can be formulated with a pharmaceutically acceptable carrier into pharmaceutical compositions. The compounds can be made by reacting the compound of formula (II) with hydroxylamine or a derivative thereof of the following formula (III) H2NOR , or with a semicarbazide or thiosemicarbazide or a hydrazine derivative of the following formula (IV) H2NNR R , or by a reaction of a compound of formula (I) where R is OH with an acylating agent of the following formula (VI): ACOR or (VII): ClCOOR .
Abstract translation: 通式（I）的化合物具有有价值的药物特性，特别是用于治疗中枢和周围神经系统中的一些干扰。 化合物可以用药学上可接受的载体配制成药物组合物。 化合物可以通过使式（II）化合物与下式（III）H 2 NOR 2的羟胺或其衍生物或与氨基脲或氨基硫脲或下式（Ⅳ）的肼衍生物H2NNR 或通过其中R为OH的式（I）化合物与下式（VI）的酰化剂：ACOR 1或（VII）：ClCOOR 1的反应。
-
公开(公告)号：WO2018076108A1
公开(公告)日：2018-05-03
申请号：PCT/CA2017/051269
申请日：2017-10-24
Applicant: UTI LIMITED PARTNERSHIP
Inventor： YONG, Voon Wee , FAISSNER, Simon , KOCH, Marcus , MICHAELS, Nathan James
IPC: A61K31/55 , A61K31/404 , A61K31/4706 , A61K31/65 , A61P21/00 , A61P25/28 , C07C225/20 , C07D209/08 , C07D215/46 , C07D223/28
Abstract: ABSTRACT In one aspect, there is provided a method of treating, prophylaxis, or amelioration of a neurological disease by administering to a subject in need thereof one or more compounds described herein. In a specific example, the neurological disease is multiple sclerosis (also referred to as "MS"). - 78 -
Abstract translation: 摘要一方面，提供了通过向有需要的受试者施用一种或多种本文所述的化合物来治疗，预防或改善神经疾病的方法。 在具体的例子中，神经疾病是多发性硬化症（也称为“MS”）。 - 78 -
-
公开(公告)号：WO2013171484A1
公开(公告)日：2013-11-21
申请号：PCT/GB2013/051248
申请日：2013-05-15
Applicant: UNIVERSITY OF BRADFORD
Inventor： KULKARNI, Chaitrali , DHUMAL, Ravindra , KELLY, Adrian , GOUGH, Tim , PARADKAR, Anant
IPC: C07D223/28 , C07C311/58 , C07D493/08 , C07D207/27 , B29B7/00 , B29C47/00
CPC classification number: B01F7/081 , B01F2215/0032 , C07C303/42 , C07C311/58 , C07D207/27 , C07D223/26 , C07D223/28 , C07D493/08 , C07D493/18
Abstract: The present invention relates to a method useful for forming products which are useful in a pharmaceutical context, and products formed by such a method. The invention relates particularly, but not exclusively, to methods of forming a metastable polymorph using screw extrusion, whereby temperature and shear induce transformational changes, and products obtained or obtainable via such methods.
Abstract translation: 本发明涉及一种可用于形成可用于制药背景的产品的方法，以及通过这种方法形成的产品。 本发明特别涉及但不排他地涉及使用螺杆挤出形成亚稳态多晶型物的方法，由此温度和剪切引起转化变化，以及通过这些方法获得或可获得的产物。
-
9.发明申请PROCESS FOR THE PREPARATION AND PURIFICATION OF ESLICARBAZEPINE ACETATE AND INTERMEDIATES THEREOF 审中-公开制备和提纯醋酸苯扎西泮及其中间体的方法
公开(公告)号：WO2013008194A2
公开(公告)日：2013-01-17
申请号：PCT/IB2012/053550
申请日：2012-07-11
Applicant: RANBAXY LABORATORIES LIMITED , HIRPARA, Ketan , KHANDURI, Chandra, Has , SHARMA, Mukesh, Kumar
Inventor： HIRPARA, Ketan , KHANDURI, Chandra, Has , SHARMA, Mukesh, Kumar
IPC: C07D223/28
CPC classification number: C07D223/28
Abstract: The present invention provides a novel process for the preparation of 10-oxo-10,11-dihydro-5 H -dibenzo[ b,f ]azepine-5-carboxamide, commonly known as oxcarbazepine, which is a medicament and a useful intermediate in the preparation of eslicarbazepine acetate. The present invention further provides a process for the preparation and purification of eslicarbazepine acetate.
Abstract translation: 本发明提供了制备10-氧代-10,11-二氢-5H-二苯并[b，f]的新方法， ]氮杂卓-5-甲酰胺，通常称为奥卡西平，它是制备醋酸艾利卡西平的药物和有用的中间体。 本发明进一步提供了制备和纯化醋酸艾塞利西平的方法。
-
10.发明申请AN IMPROVED PROCESS FOR THE PREPARATION OF OXCARBAZEPINE AND RELATED INTERMEDIATES 审中-公开改进奥沙利铂及相关中间体的制备方法
公开(公告)号：WO2005122671A3
公开(公告)日：2007-11-08
申请号：PCT/CA2005000932
申请日：2005-06-16
Applicant: APOTEX PHARMACHEM INC , CHE DAQING , CORELLI-RENNIE NADIA , GUNTOORI BHASKAR REDDY , FAUGHT JODY
Inventor： CHE DAQING , CORELLI-RENNIE NADIA , GUNTOORI BHASKAR REDDY , FAUGHT JODY
IPC: C07D223/22 , A61K31/55 , C07D223/18 , C07D223/26 , C07D223/28 , C07D223/30
CPC classification number: C07D223/26 , C07D223/28
Abstract: A process for preparing Oxcarbazepine III comprising: a) reacting oximinostilbene IV with chlorosulfonyl isocyanate in an inert organic solvent and isolating compound V b) hydrolyzing compound V to form crude Oxcarbazepine III c) purifying oxcarbazepine.
Abstract translation: 一种制备奥卡西平III的方法，包括：a）使肟基芪Ⅳ与氯磺酰异氰酸酯在惰性有机溶剂中反应，并分离化合物Ⅴb）水解化合物V以形成粗制的奥卡西平III，c）纯化奥卡西平。
-
-
-
-
-
-
-
-
-
Search Results
46
records
(took 0.011 seconds)
