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Invention Application
WO2016044167A1 METHODS FOR INCREASING MUSCLE STRENGTH AND MOBILITY IN SUBJECTS EXPERIENCING SIGNIFICANT PHYSICAL INACTIVITY USING GAMMA LINOLENIC ACID 审中-公开
增加肌肉强度和运动能力的方法使用游离氨基酸处理重要的物理活性

  • Patent Title: METHODS FOR INCREASING MUSCLE STRENGTH AND MOBILITY IN SUBJECTS EXPERIENCING SIGNIFICANT PHYSICAL INACTIVITY USING GAMMA LINOLENIC ACID
  • Patent Title (中): 增加肌肉强度和运动能力的方法使用游离氨基酸处理重要的物理活性
  • Application No.: PCT/US2015/049990
    Application Date: 2015-09-14
  • Publication No.: WO2016044167A1
    Publication Date: 2016-03-24
  • Inventor: PEREIRA, Suzette , EDENS, Neile , DEMICHELE, Stephen
  • Applicant: ABBOTT LABORATORIES
  • Applicant Address: Dept. 377/AP6A-1 100 Abbott Park Road Abbott Park, Illinois 60064 US
  • Assignee: ABBOTT LABORATORIES
  • Current Assignee: ABBOTT LABORATORIES
  • Current Assignee Address: Dept. 377/AP6A-1 100 Abbott Park Road Abbott Park, Illinois 60064 US
  • Agency: BRADY, J et al.
  • Priority: US62/050,346 20140915
  • Main IPC: A23L1/30
  • IPC: A23L1/30 ;  A61K31/202 ;  A61P21/00
METHODS FOR INCREASING MUSCLE STRENGTH AND MOBILITY IN SUBJECTS EXPERIENCING SIGNIFICANT PHYSICAL INACTIVITY USING GAMMA LINOLENIC ACID
Abstract:
Methods of increasing muscle strength and mobility in a subject experiencing significant physical inactivity include administering gamma linolenic acid to the subject as part of a nutritional composition containing fat and at least one of protein and carbohydrate. Administration of the nutritional composition to the subject increases muscle strength and mobility of the subject by increasing levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) in muscle of the subject.
Abstract(Chinese):

在经历显着身体不活动的受试者中增加肌肉力量和移动性的方法包括向受试者施用γ-亚麻酸，作为含有脂肪和至少一种蛋白质和碳水化合物的营养组合物的一部分。 通过增加受试者肌肉中过氧化物酶体增殖物激活的受体γ共激活因子-1α（PGC-1α）的水平，对受试者施用营养组合物增加受试者的肌肉力量和流动性。

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