公开(公告)号：WO2015126716A1

公开(公告)日：2015-08-27

申请号：PCT/US2015/015566

申请日：2015-02-12

Applicant: ABBOTT LABORATORIES

Inventor： MEADOR, Benjamin ,  PEREIRA, Suzette ,  EDENS, Neile ,  PATEL, Gaurav

IPC: A23L1/30 ,  A23L1/305 ,  A23L2/52 ,  A23L2/66

CPC classification number: A23L2/52 ,  A23L2/66 ,  A23L33/10 ,  A23L33/105 ,  A23L33/17

Abstract: A liquid nutritional composition includes a source of epigallocatechin gallate and at least one of a source of protein, a source of carbohydrate, and a source of fat. The liquid nutritional composition includes gallocatechin gallate and epigallocatechin gallate in a ratio of about 1:20 to about 1:0.60. At least a portion of the gallocatechin gallate is formed by epimerization of the epigallocatechin gallate as a result of application of heat to the liquid nutritional composition. Methods of making the liquid nutritional composition are also provided.

Abstract translation: 液体营养组合物包括表没食子儿茶素没食子酸酯的来源和蛋白质来源，碳水化合物源和脂肪源中的至少一种。 液体营养组合物包含比例为约1:20至约1:0.60的没食子儿茶素没食子酸酯和表没食子儿茶素没食子酸酯。 通过向液体营养组合物施加热量，表儿茶素没食子酸酯的至少一部分由表没食子儿茶素没食子酸酯的差向异构化形成。 还提供了制备液体营养组合物的方法。

公开(公告)号：WO2015089009A1

公开(公告)日：2015-06-18

申请号：PCT/US2014/069215

申请日：2014-12-09

Applicant: ABBOTT LABORATORIES

Inventor： WEARLY, Douglas ,  JOHNS, Paul ,  DEWILLE, Normanella ,  BLUMBERG, Rachel ,  BAXTER, Jeffrey

IPC: A23L1/305 ,  A23C9/156 ,  A23L2/39 ,  A23L2/66 ,  A23L1/00 ,  A23L1/29

CPC classification number: A23L2/66 ,  A23L2/52 ,  A23L33/115 ,  A23L33/125 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00

Abstract: The combination of potato protein, intact rice protein and hydrolyzed rice protein, replaces a portion of the vegetable protein in a nutrition shake or other nutritional composition intended for oral consumption. By suitable selection of the types and amounts of these proteins the overall cost of manufacturing the nutritional composition can be reduce without adversely affecting its other desirable properties such as nutritional value, stability, taste and mouthfeel.

Abstract translation: 马铃薯蛋白质，完整的米蛋白质和水解的蛋白质的组合替代了用于口服消费的营养摇动剂或其它营养组合物中的一部分植物蛋白质。 通过适当选择这些蛋白质的类型和量，可以减少营养组合物的总体成本，而不会不利地影响其它所需的性质，例如营养价值，稳定性，味觉和口感。

公开(公告)号：WO2016044167A1

公开(公告)日：2016-03-24

申请号：PCT/US2015/049990

申请日：2015-09-14

Applicant: ABBOTT LABORATORIES

Inventor： PEREIRA, Suzette ,  EDENS, Neile ,  DEMICHELE, Stephen

IPC: A23L1/30 ,  A61K31/202 ,  A61P21/00

CPC classification number: A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A23V2200/316 ,  A23V2250/1874 ,  A23V2250/54 ,  A61K2300/00

Abstract: Methods of increasing muscle strength and mobility in a subject experiencing significant physical inactivity include administering gamma linolenic acid to the subject as part of a nutritional composition containing fat and at least one of protein and carbohydrate. Administration of the nutritional composition to the subject increases muscle strength and mobility of the subject by increasing levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) in muscle of the subject.

Abstract translation: 在经历显着身体不活动的受试者中增加肌肉力量和移动性的方法包括向受试者施用γ-亚麻酸，作为含有脂肪和至少一种蛋白质和碳水化合物的营养组合物的一部分。 通过增加受试者肌肉中过氧化物酶体增殖物激活的受体γ共激活因子-1α（PGC-1α）的水平，对受试者施用营养组合物增加受试者的肌肉力量和流动性。

公开(公告)号：WO2015095570A3

公开(公告)日：2015-06-25

申请号：PCT/US2014/071236

申请日：2014-12-18

Applicant: ABBOTT LABORATORIES

Inventor： JOHNS, Paul ,  NEAL, Cynthia ,  MCEWEN, John ,  MCKENNA, Ronald

IPC: A23L1/30 ,  A23L1/302 ,  A23L1/304 ,  A23L1/305 ,  A23L1/29 ,  A61K31/202 ,  A61P3/04

Abstract: Liquid nutritional compositions include specific combinations of protein, carbohydrate, and fat for the nutritional support of individuals with particular needs, such as individual suffering from obesity. The compositions comprise a source of at least one omega-6 fatty acid and a source of at least one omega-3 fatty acid with a ratio of omega-6 to omega-3 of 1:5 to 1:1. In a preferred form the compositions comprise at least one hydrolysed dairy protein selected from hydrolysed whey protein and hydrolysed casein protein or mixtures thereof. Methods of administering such nutritional compositions are also provided. Further liquid nutritional compositions comprise protein in an amount of 1-12% by weight of the liquid nutritional composition, vitamin C and copper, wherein the protein comprises a mixture of whey protein and casein with a majority of the whey protein having a degree of hydrolysis greater than 20%. Methods for improving vitamin C stability in these liquid nutritional compositions are also provided.

公开(公告)号：WO2015095545A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/071200

申请日：2014-12-18

Applicant: ABBOTT LABORATORIES

Inventor： TERP, Megan ,  HEO, Youngsuk ,  DEWILLE, Normanella

IPC: A23L2/44 ,  A23L3/3454 ,  A23C3/08 ,  A23L1/30

CPC classification number: A23L33/40 ,  A23C3/08 ,  A23D7/0053 ,  A23D7/011 ,  A23D7/06 ,  A23L2/44 ,  A23L3/3454 ,  A23L27/84 ,  A23L33/105 ,  A23L33/115 ,  A23L33/12 ,  A23L33/125 ,  A23L33/17 ,  A23V2002/00 ,  A23V2200/02 ,  A23V2250/21

Abstract: A nutritional composition including an oxidizable oil and rosmarinic acid is provided. The rosmarinic acid protects the flavor and aroma of the nutritional composition by reducing oxidation of the oxidizable oil and reducing or otherwise masking off-flavors and aromas.

Abstract translation: 提供了包含可氧化油和迷迭香酸的营养组合物。 迷迭香酸通过减少可氧化油的氧化并减少或以其他方式掩蔽异味和香味来保护营养组合物的风味和香气。

公开(公告)号：WO2016029074A1

公开(公告)日：2016-02-25

申请号：PCT/US2015/046208

申请日：2015-08-21

Applicant: ABBOTT LABORATORIES

Inventor： WEARLY, Douglas ,  DEWILLE, Normanella ,  BLUMBERG, Rachel

IPC: A23L1/305 ,  A23L1/29 ,  A23L2/39

CPC classification number: A23L2/39 ,  A23L33/185 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/3202 ,  A23V2200/3204 ,  A23V2250/0612 ,  A23V2250/0644 ,  A23V2250/156 ,  A23V2250/1882 ,  A23V2250/5046 ,  A23V2250/54246 ,  A23V2250/54252 ,  A23V2250/548 ,  A23V2250/70

Abstract: Protein systems useful in nutritional compositions are disclosed. By suitable selection of the types and amounts of vegetable protein, for example rice protein, in the protein system the overall cost of manufacturing the nutritional composition can be reduced without adversely affecting its other desirable properties such as nutritional value, stability, solubility, taste, and mouthfeel.

Abstract translation: 公开了可用于营养组合物的蛋白质系统。 通过适当选择植物蛋白（例如大米蛋白）的类型和量，在蛋白质系统中，可以降低制造营养组合物的总体成本，而不会不利地影响其它所需的性质，例如营养价值，稳定性，溶解度，味道， 和口感。

公开(公告)号：WO2015095725A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/071539

申请日：2014-12-19

Applicant: ABBOTT LABORATORIES

Inventor： TIAN, Min ,  PEREIRA, Suzette ,  MUSTAD, Vikkie ,  CRAMER, Joel

IPC: A23L1/30 ,  A23L1/29

CPC classification number: A23L33/115 ,  A23L33/10 ,  A23L33/30 ,  A23L33/40

Abstract: Methods and nutritional compositions are disclosed for attenuating muscle protein degradation, preserving lean body mass, or both in a subject in need thereof. Generally, the nutritional composition includes a source of fat, a source of protein, a source of carbohydrate, a source of β-hydroxy-β-methylbutyrate, at least one polyunsaturated fatty acid, at least one monounsaturated fatty acid, at least one vitamin, and at least one mineral. The nutritional composition also generally has from 10 grams to 25 grams of protein and from 240 kcal to 500 kcal per serving.

Abstract translation: 公开的方法和营养组合物用于减弱需要的受试者的肌肉蛋白质降解，保持瘦体重或两者。 通常，营养组合物包括脂肪源，蛋白质来源，碳水化合物源，β-羟基-β-甲基丁酸酯源，至少一种多不饱和脂肪酸，至少一种单不饱和脂肪酸，至少一种维生素 ，和至少一种矿物。 营养组合物还通常具有10克至25克蛋白质和240克卡至500千卡/份。

公开(公告)号：WO2015095542A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/071197

申请日：2014-12-18

Applicant: ABBOTT LABORATORIES

Inventor： LOWE, Kelley ,  CHAPMAN, Timothy ,  DEWILLE, Normanella ,  WEARLY, Douglas

IPC: A23L1/30 ,  A23L1/305

CPC classification number: A23L33/40 ,  A23L29/015 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/17 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23V2002/00

Abstract: A translucent, high acid, low viscosity, high caloric density liquid nutritional composition and methods of making the liquid nutritional composition are provided. The liquid nutritional composition is translucent and has a viscosity of 25 to 100 centipoise, a caloric density of 50 to 200 kcal per 100 mL, and a pH of 2 to 4.6.

Abstract translation: 提供半透明，高酸，低粘度，高热量密度的液体营养组合物和制备液体营养组合物的方法。 液体营养组合物是半透明的，粘度为25-100厘泊，热密度为每100毫升50至200千卡，pH为2至4.6。

公开(公告)号：WO2015094772A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/069126

申请日：2014-12-08

Applicant: ABBOTT LABORATORIES

Inventor： MEADOR, Benjamin ,  PEREIRA, Suzette ,  EDENS, Neile ,  TISDALE, Michael

IPC: A23L1/30 ,  A23L1/29 ,  A61K31/353 ,  A61P21/00

CPC classification number: A61K31/353 ,  A23L33/105 ,  A23L33/115 ,  A23L33/125 ,  A23L33/17 ,  A23L33/30 ,  A23V2002/00 ,  A23V2200/316 ,  A23V2250/214 ,  A61K9/0053 ,  A61K31/19 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods of increasing skeletal muscle protein synthesis in a subject are provided. Methods of increasing or maintaining mammalian target of rapamycin (mTOR) activation are also provided. Such methods include a step of administering at least one serving per day of a composition including 20 to 2,000 mg of a green tea extract per serving to the subject.

Abstract translation: 提供了在受试者中增加骨骼肌蛋白质合成的方法。 还提供了增加或维持哺乳动物雷帕霉素靶标（mTOR）活化的方法。 这样的方法包括每天给予至少一份服用组合物的步骤，其包含20至2,000mg每份一份绿茶提取物。

公开(公告)号：WO2021173997A1

公开(公告)日：2021-09-02

申请号：PCT/US2021/019908

申请日：2021-02-26

Applicant: ABBOTT LABORATORIES

Inventor： LÓPEZ PEDROSA, José María ,  MANZANO MARTÍN, Manuel ,  RUEDA CABRERA, Ricardo

IPC: A23L33/125 ,  A23L33/21 ,  A23L33/24 ,  A23L33/00 ,  A61K31/7016 ,  A61K31/702 ,  A61K31/715 ,  A23L33/115 ,  A23L33/18 ,  A23L33/30 ,  A23V2002/00 ,  A61P19/00 ,  A61P3/02

Abstract: A method of promoting bone health in a moderately malnourished individual is provided. The method includes treating the moderately malnourished individual with a nutritional composition that contains a carbohydrate blend. The carbohydrate blend includes a source of at least one carbohydrate that provides rapidly available glucose, a source of at least one carbohydrate that provides slowly available glucose, and a source of at least one non-digestible carbohydrate or resistant starch.